improvements in the two-step synthesis of 1,1,1,3,3,3-hexafluoro-2- (fluoromehoxy)propane (sevoflurane) that result in the product cost reduction, safety level enhancement and positive environmental impacts are described. this process consists of chloromethylation reaction of 1,1,1,3,3,3-hexafluoro-2-propanol (hfip) followed by a halogen-exchange fluorination. this is the first synthesis of sev...