Antipsychotics are often administered to traumatic brain injured (TBI) patients as a means of controlling agitation, albeit the rehabilitative consequences of this intervention are not well known. Hence, the goal of this study was to evaluate the effects of risperidone (RISP) and haloperidol (HAL) on behavioral outcome after experimental TBI. Anesthetized rats received either a cortical impact ...

MOTIVATION Large multiple genome alignments and inferred ancestral genomes are ideal resources for comparative studies of molecular evolution, and advances in sequencing and computing technology are making them increasingly obtainable. These structures can provide a rich understanding of the genetic relationships between all subsets of species they contain. Current formats for storing genomic a...

s for enhanced information access. Fidelia Ibekwe-Sanjuan To cite this version: Fidelia Ibekwe-Sanjuan. Semantic metadata annotation. Tagging Medline abstracts for enhanced information access.. Aslib Proceedings, Emerald, 2010, 62 (4/5), pp.476-488. . HAL Id: hal-00635288 https://hal.archives-ouvertes.fr/hal-00635288 Submitted on 24 Oct 2011 HAL is a multi-disciplinary open access archive for t...

nonconforming error estimates and application to boundary penalty methods for diffusion equations and time-harmonic Maxwell’s equations Alexandre Ern, Jean-Luc Guermond To cite this version: Alexandre Ern, Jean-Luc Guermond. Abstract nonconforming error estimates and application to boundary penalty methods for diffusion equations and time-harmonic Maxwell’s equations. 2017. HAL Id: hal-01563594...

Purpose We evaluated improvements in gait after using the Hybrid Assistive Limb (HAL®) exoskeleton robot in a patient with late-onset neurological deterioration of lower extremity function after undergoing thoracic spine surgery for a myelopathy due to ossification of the ligamentum flavum. Case Presentation A 70-year-old man participated in ten 20 min sessions of HAL intervention, twice week...

The selection of appropriate substrates for investigating the potential inhibition of CYP3A4 is critical as the magnitude of effect is often substrate-dependent, and a weak correlation is often observed among different CYP3A4 substrates. This feature has been attributed to the existence of multiple binding sites and, therefore, relatively complex in vitro data modeling is required to avoid erro...

Dysfunction of the N-methyl-d-aspartate (NMDA) receptor has been implicated in the pathogenesis of schizophrenia. Although agonists for the glycine-binding sites of NMDA receptors have potential as new medication for schizophrenia, their modulation of antipsychotic-induced extrapyramidal side effects (EPS) has not yet been clarified. We herein evaluated the effects of glycine-binding site stimu...

In two experiments, we attempted to replicate and extend findings by Günther et al. (2016) that word similarity measures obtained from distributional semantics models-Latent Semantic Analysis (LSA) and Hyperspace Analog to Language (HAL)-predict lexical priming effects. To this end, we used the pseudo-random method to generate item material while systematically controlling for word similarities...

BACKGROUND People with hemophilia (PWH) experience frequent joint bleeding, resulting in pain and functional impairment. Generic and disease-specific patient-reported outcome (PRO) instruments have been used in clinical studies, but rarely in the comprehensive hemophilia care setting. OBJECTIVE The objective of this study was to assess construct validity of PRO instruments measuring pain, fun...