We evaluated a novel scintigraphic method using new parameters of mechanical left ventricular (LV) dyssynchrony and correlated it with clinical outcomes in heart failure patients with reduced ejection fraction receiving cardiac resynchronization therapy (CRT). METHODS Sixty-six advanced heart failure patients referred for CRT with an LV ejection fraction (EF) of < 35% and QRS ≥ 120 ms were st...

β-Thalassemia (β-thal) is a major public health problem in Albania as it is in many Mediterranean countries. We determined the different β-thal alleles that are present in the Albanian population by using the temporal temperature gradient electrophoresis (TTGE) method because of its high throughput, cost-effectiveness, sensitivity and simplicity. DNA from blood of 68 patients with β-thal, 26 wi...

Left ventricular hypertrophy (LVH) is an important predictor of cardiovascular morbidity and mortality. To investigate the feasibility of the myocardial grayscale intensity (GI) normalized by displacement (d) to discriminate between healthy and hypertrophic myocardium in hypertensive patients, sixty hypertensive patients and sixty age and sex-matched healthy volunteers were involved in this stu...

AIMS To determine the presence and extent of delayed contrast enhancement (DCE) in patients with pulmonary hypertension (PHT) using contrast enhanced-cardiovascular magnetic resonance imaging (ce-CMR). METHODS AND RESULTS Twenty-five patients with PHT underwent ce-CMR and right heart catheterization. Right ventricular (RV) and left ventricular (LV) volumes, ejection fraction, mass, and DCE ma...

β-Thalassemia is the most common inherited disorder in Azerbaijan. The aim of our study was to reveal genotype-to-phenotype correlations of the most common β-thalassemia mutations in an Azerbaijani population. Patients with codon 8 (-AA), IVS-I-6 (T>C), and IVS-II-1 (G>A) mutations, which are reportedly the most common β-globin gene mutations among the local population, were tested for hematolo...

Biham and Seberry have submitted the stream cipher Py and Pypy to the ECRYPT stream cipher project (eSTREAM). A key recovery attack against Py and Pypy was proposed by Wu and Preneel. In their attack, (IV sizeb − 9) bytes of the key can be recovered with (IV sizeb − 4) × 2 chosen IVs, where IV sizeb indicates the size of the IV in bytes. For a 128-bit key and a 128-bit IV, which are recommended...

The intervening sequence (IVS) excised from the rRNA precursor of Tetrahymena thermophila is converted to a covalently closed circular RNA in the absence of proteins in vitro. This self-catalyzed cyclization reaction is inhibited by the intercalating dye methidiumpropyl.EDTA (MPE; R.P. Hertzberg and P.B. Dervan (1982) J. Am. Chem. Soc. 104, 313-315). The MPE binding sites have been localized by...

Pulmonary atresia with intact ventricular septum (PA-IVS) is a complex congenital heart malformation with a diverse set of anatomical and clinical findings. The incidence is 4.1 per 100,000 live births and is less than 1% of all congenital heart disease. During embryogenesis, PA-IVS is postulated to occur after development of ventricular septum which is later than the development of PA with ven...

An input-series output-parallel (ISOP) system, in which multiple converter modules are connected in series at the input sides and parallel at the output side, is very suitable for high input-voltage, low output-voltage, and high output-current applications. Input-voltage sharing (IVS) and output-current sharing of the constituent modules among the ISOP system must be ensured. The existing IVS c...

The Intelligent vehicle (IV) is experiencing revolutionary growth in research and industry, but it still suffers from many security vulnerabilities. Traditional security methods are incapable to provide secure IV communication. The major issues in IV communication, are trust, data accuracy and reliability of communication data in the communication channel. Blockchain technology works for the cr...