This paper studies drawdown and drawup processes in a general diffusion model. The main result is a formula for the joint distribution of the running minimum and the running maximum of the process stopped at the time of the first drop of size a. As a consequence, we obtain the probabilities that a drawdown of size a precedes a drawup of size b and vice versa. The results are applied to several ...

This paper asks whether neuroeconomics will make instrumental use of neuroscience to adjudicate existing disputes in economics or be more seriously informed by neuroscience in ways that might transform economics. The paper pursues the question by asking how neuroscience constructs an understanding of individuals as whole persons. The body of the paper is devoted to examining two approaches: Don...

In this work, we analyze two important and simple models of short rates, namely Vasicek and CIR models. The models are described and then the sensitivity of the models with respect to changes in the parameters are studied. Finally, we give the results for the estimation of the model parameters by using two different ways.

T he term structure models discussed in our previous article (“Term Structure of Interest Rates,” MiER Vol. 7, No. 3) such as the [Vasicek 1978] or the [CoxIngersoll-Ross 1985] model may not match the current term structure. The Black-Derman-Toy (BDT) and BlackKarasinksi models discussed in this article are important examples of models in which the current term structure can always be replicated.

Despite the considerable range of newly identified disease modifying approaches to the control of the inflammatory process reported over the past 10–20 years, only a few have yet gained widespread clinical acceptance. In contrast, the very recent advent of the class of anti-inflammatory agents termed COX-2 selective inhibitors is already having a significant impact on current clinical prescribi...

background: kidney transplantation is the best alternative treatment for end-stage renal disease. several studies have been devoted to investigate predisposing factors of graft rejection. however, there is inconsistency between the results. the objective of the present study was to utilize an intuitive and robust approach for variable selection, random survival forests (rsf), and to identify im...

background: no data is available on morphology and genetic characteristics of echinococcus granulosus derived from donkeys of iran, despite of its existence in donkeys.in the present study morphometric variations of the rostellar hooks of protoscoleces and genotype characteristics of hydatid cyst of donkey from iran were determined. methods: protoscoleces prepared from hydatid cyst of donkey of...

background : the aim of this study was to predict the survival rate of iranian gastric cancer patients using the cox proportional hazard and artificial neural network models as well as comparing the ability of these approaches in predicting the survival of these patients. methods: in this historical cohort study, the data gathered from 436 registered gastric cancer patients who have had surgery...