External beam radiotherapy is commonly used for patients with cancer. While tumor shrinkage and palliation are frequently achieved, local control and cure remain elusive for many cancers. With regard to local control, the fundamental problem is that radiotherapy-induced normal tissue injury limits the dose that can be delivered to the tumor. While intensity-modulated radiation therapy (IMRT) al...

We still lack operative and theoretically founded definitions of what a personality disorder (PD) is, as well as empirically validated and feasible instruments to measure the disorder construct. The Temperament and Character Inventory (TCI) is the only personality instrument that explicitly distinguishes personality style and disordered functioning. Here, we seek to (1) confirm in a clinical sa...

Transcutaneous immunization (TCI) capitalizes on the accessibility and immunocompetence of the skin, elicits protective immunity, simplifies vaccine delivery, and may be particularly advantageous when frequent boosting is required. In this study we examined the potential of TCI to boost preexisting immune responses to diphtheria in mice. The cross-reacting material (CRM(197)) of diphtheria toxi...

Transported probability density function (PDF) methods are used to account for turbulent fluctuations in composition and temperature in simulations of liquid fuel injection (n-heptane), vaporization, mixing, autoignition, combustion and soot formation for a constant-volume combustion chamber. Both stochastic Lagrangian particle and stochastic Eulerian field methods are used to solve the modeled...

The aim of this study was to compare the psychometric properties (normal distribution values, reliabilities and factor structure) of the Zuckerman-Kuhlman-Aluja Personality Questionnaire (ZKA-PQ) and the Temperament and Character Inventory revised (TCI-R). The total sample consisted of 482 subjects (53.1% men and 46.9% women) from diverse age. Results showed somewhat better psychometric propert...

Purpose: Appropriate sedation is required when performing proton radiation therapy on pediatric patients. A target-controlled infusion (TCI) of propofol has recently been used for this purpose. However, there may be safety issues with the use of TCI in pediatric patients, as the initial bolus dose might be excessive for younger patients. To compare the safety and the incidence of adverse events...

The aim of the experiment was to verify the efficacy of the treatment of psoroptic mange in a flock of Churra sheep farmed under organic production conditions, using alternative methods. One group, C Control (N=9), was given no treatment, a second group, TAH Antihomotoxic (N=10), was intramuscularly administered an antihomotoxic preparation every two days, thus receiving a total of seven inject...

Abstract Tourism is a highly climate-sensitive sector, and the suitability of climate weather can be central motivation for travel. Through tourism index (TCI), this study uses daily data from period 1980 to 2014 identify spatial temporal distribution climatic conditions in Xinjiang China with regard its attractiveness general tourism. The analytical results indicate that most suitable months a...

Human personality traits have a considerable genetic component. Cloninger et al. were the first to postulate that certain personality traits, such as novelty seeking, are related to the dopamine neurotransmitter system. In this study, we investigated the associations between dopamine receptor D4 (DRD4) exon III and dopamine transporter (DAT1) polymorphisms and personality traits. The DRD4 and D...