Characterization of the different lymphocyte populations in normal human bone marrow (BM) was attempted and compared to that in the peripheral blood (PB). B cells comprised 34% +/- 11% of lymphocytes in BM and 23% +/- 9% in PB. The majority of B cells carried IgM in BM and IgG in the PB. In the BM, cells carrying complement or Fc receptors were fewer than cells carrying Ig, but in the PB they w...

Business model (BM) innovation for sustainability is hampered by a lack of tools environmental assessment and guidance at the BM level. Conventional life cycle (LCA) neglects economic socio-technical mechanisms within BM, based on canvas (BMC) cannot provide recommendations substantiated data. Here, new method, BM-LCA, applied to case comparing selling renting jackets, using profit as basis com...

BACKGROUND The prognostic impact of the presence of differentiating neuroblasts in bone marrow (BM) remains unclear in BM metastatic neuroblastoma (NB). We aimed to identify the prognostic impact of differentiating neuroblasts in BM at diagnosis and after chemotherapy. METHODS A total of 51 patients diagnosed with BM metastatic NB at Asan Medical Center between January 1990 and July 2005 were...

PURPOSE Bone-marrow (BM)-derived hematopoietic precursor cells are thought to participate in the growth of blood vessels during postnatal vasculogenesis. In this investigation, multichannel laser scanning confocal microscopy and quantitative image analysis were used to study the fate of BM-derived hematopoietic precursor cells in corneal neovascularization. METHODS A BM-reconstituted mouse mo...

objective(s): nowadays much effort is being invested in order to diagnose the mechanisms involved in neural differentiation. by clarifying this, making desired neural cells in vitro and applying them into diverse neurological disorders suffered from neural cell malfunctions could be a feasible choice. thus, the present study assessed the capability of fetal brain extract (fbe) to induce rat bon...

background infertility is a serious social problem in advanced nations, with male factor in half of all cases of infertility. this study was conducted to determine the regenerative effect of bone marrow-derived stem cells in spermatogenesis of infertile hamster. methods twelve adult male hamsters were equally divided into azoospermic and control groups. busulfan was intraperitoneally used for i...

background: langerhans' cell histiocytosis (lch) is a reactive proliferative disease of unknown pathogenesis characterized by proliferation of langerhans cells. involvement of bone marrow (bm), liver and lung are related to high risk factors and poor survival. the aim of this report is to highlight the clinical and haematological findings of 5 cases of lch with bm infiltration which may help to...

BACKGROUND AND OBJECTIVE CD34+ hematopoietic progenitor cells (HPCs) constitute a heterogeneous population both in size and in immunological features. Lack of CD38, HLA-DR and lineage committed antigens as well as the co-expression of Thy-1 (CDw90) and c-kit receptor (CD117), are able to identify the so-called stem cells. A flow cytometric study was carried out to investigate the co-expression ...

It remains elusive as to what bone marrow (BM) cell types infiltrate into injured and/or diseased tissues and subsequently differentiate to assume the phenotype of residential cells, for example, neurons, cardiac myocytes, keratocytes, etc., to repair damaged tissue. Here, we examined the possibility of whether BM cell invasion via circulation into uninjured and injured corneas could assume a k...

The use of dendritic cells (DCs) loaded with tumour antigen is one of the most promising approaches to induce tumour-specific immune response. However, methods of the vaccine preparation have not yet been standardized. The purpose of the study was to analyse the anti-tumour efficacy of tumour antigen-loaded mouse bone marrow-derived dendritic cells (BM-DC/TAg) at different maturation stages. BM...