The K(+) channel mKv1.5 is thought to encode a 4-aminopyridine (4-AP)-sensitive component of the current I(K,slow) in the mouse heart. We used gene targeting to replace mKv1.5 with the 4-AP-insensitive channel rKv1.1 (SWAP mice) and directly test the role of Kv1.5 in the mouse ventricle. Kv1.5 RNA and protein were undetectable, rKv1.1 was expressed, and Kv2.1 protein was upregulated in homozygo...

Addressing SWaP Challenges in Military Platforms With 65-nm FPGAs and Structured ASICs Introduction Now more than ever, size, weight, and power (SWaP) must be managed and reduced across virtually all military and aerospace applications to improve operational efficiency and logistics, increase mission life, and reduce the total cost of system ownership. System upgrades are driving added function...

We describe how any two-party quantum computation, specified by a unitary which simultaneously acts on the registers of both parties, can be privately implemented against a quantum version of classical semi-honest adversaries that we call specious. Our construction requires two ideal functionalities to garantee privacy: a private SWAP between registers held by the two parties and a classical pr...

Developers use various methods and approaches to find bugs and performance bottlenecks in their programs. One of the effective and widely used approach is application profiling by dynamic instrumentation. There are many various tools based on dynamic instrumentation. Each tool has its own benefits and limitations what often forces developers to use several of them for profiling. For example, in...

Order-independent (OI) queues, introduced by Berezner, Kriel, and Krzesinski in 1995, expanded the family of multi-class queues that are known to have a product-form stationary distribution allowing for intricate class-dependent service rates. This paper further broadens this introducing pass-and-swap (P&S) an extension OI where, upon completion, customer completes is not necessarily one leaves...

This paper tests a model based on Wall's (Wall, L., 1989. Journal of Banking and Finance 13, 261±270) hypothesis of agency cost reduction using interest rate swaps. We ®nd a signi®cant positive relationship between the risk of the ®rm and the reduction of agency costs measured by the continuously compounded excess return (CAR) of the ®rm. Our ®ndings are consistent with WallÕs hypothesis and ot...