The mechanism by which the self-assembling GTPase dynamin functions in vesicle formation remains controversial. Point mutations in shibire, the Drosophila dynamin, cause temperature-sensitive (ts) defects in endocytosis. We show that the ts2 mutation, which occurs in the switch 2 region of dynamin's GTPase domain, compromises GTP binding affinity. Three second-site suppressor mutations, one in ...

Easy access and vast amount of data, especially from long period of time, allows to divide social network into timeframes and create temporal social network. Such network enables to analyse its dynamics. One aspect of the dynamics is analysis of social communities evolution, i.e., how particular group changes over time. To do so, the complete group evolution history is needed. That is why in th...

The chemical industry requires highly accurate and reliable measurements to ensure smooth operation effective monitoring of processing facilities. However, measured data inevitably contains errors from various sources. Traditionally in flow systems, reconciliation through mass balancing is applied reduce error by estimating balanced flows. this approach can only handle random errors. For non-ra...

In my recent review of dynamin-related proteins, I had to admit that research on dynamin itself would continue to lead the way1. This proved true with the publication of three new articles on dynamin2–4. Two of the new articles support the role of dynamin as a mechanochemical enzyme that drives the release of clathrin-coated vesicles from the plasma membrane. This mechanochemical function was p...

The article proposes to think about theoretical aspects of the association between chil-dhood and elaboration modern lyrical subject its implications for understanding idea poetic emotion. To this end, text presents a brief journey figurations child as they emer-ged with German romanticism, passing through Baudelaire, Winnicott René Schérer, finally read figure incorporated by poetics Portugues...

Identification is the most important stage of all stages modeling process. This research identifies a suitable order for two different time series models ARIMA and GARCH. For GARCH distributions that GARCH-STD GARCH-GED with sample sizes in fitting forecasting stationary non-stationary data structures was considered. The study recommends use smallest information criterion like AIC BIC to select...

Synovial sarcoma is a primitive mesenchymal neoplasm characterized in almost all cases by a t(X;18) fusing the SYT transcriptional coactivator gene with either SSX1 or SSX2, with the resulting fusion gene encoding an aberrant transcriptional regulator. A subset of synovial sarcoma, predominantly cases with the SYT-SSX1 fusion, shows foci of morphologic epithelial differentiation in the form of ...

he mechanism by which the self-assembling GTPase dynamin functions in vesicle formation remains controversial. Point mutations in shibire , the Drosophila dynamin, cause temperature-sensitive (ts) defects in endocytosis. We show that the ts2 mutation, which occurs in the switch 2 region of dynamin’s GTPase domain, compromises GTP binding affinity. Three second-site suppressor mutations, one in ...