The objective of this study was to investigate the immunomodulatory effects of heat-killed Enterococcus faecalis TH10 (hk-TH10) and its signal transduction on murine macrophage RAW264 cells. RAW264 cells produced nitric oxide (NO) following hk-TH10 treatment. In order to investigate the mechanisms underlying hk-TH10-stimulated NO production, we further measured NO production in RAW264 cells tre...

The coordination of anti-air warfare (AAW) hardkill (HK) and softkill (SK) weapon systems is an important aspect of command and control for the HALIFAX Class Frigate. This led to the development of a rapid prototyping environment, described here, which supports the investigation of methods to coordinate the plans produced by AAW HK and SK agents. The HK and SK planning agents are described. An ...

ABSTRACT Spectropolarimetric data allow for simultaneous monitoring of stellar chromospheric $\log {R^{\prime }_{\rm {HK}}}$ activity and the surface-averaged longitudinal magnetic field, Bl, giving opportunity to probe relationship between large-scale fields manifestations magnetism. We present and/or Bl measurements 954 mid-F mid-M stars derived from spectropolarimetric observations contained...

Thromb Haemost 2007; 98: 77–83 For forty years my laboratory has been studying the kallikrein-kininogen-kinin system (KKS). I was challenged by my mentor Dr. Sol Sherry in whose laboratory I was completing my postdoctoral fellowship in 1966–1967 to find out what major plasma esterase was being activated by exposure of plasma to glass beads. Although both factors XII and XI were candidates, neit...

The Hellinger-Kantorovich (HK) distance is an unbalanced extension of the Wasserstein-2 distance. It was shown recently that HK barycenter exhibits a much more complex behaviour than Wasserstein barycenter. Motivated by this observation we study in detail for case where input measures are uncountable collection Dirac measures, particular dependency on length scale parameter HK, question whether...

H. F. Chau, ∗ Chi-Kwong Li, † Yiu-Tung Poon, ‡ and Nung-Sing Sze § Department of Physics and Center of Theoretical and Computational Physics, University of Hong Kong, Pokfulam Road, Hong Kong Department of Mathematics, College of William & Mary, Williamsburg, VA 23187-8795, USA¶ Department of Mathematics, Iowa State University, Ames, IA 50011, USA Department of Applied Mathematics, The Hong Kon...

Proteolytic cleavage of single-chain, high molecular weight kininogen (HK) by kallikrein releases the short-lived vasodilator bradykinin and leaves behind a two-chain, high molecular weight kininogen (HKa) reported to bind to the beta2-integrin Mac-1 (CR3, CD11b/CD18, alphaMbeta2) on neutrophils and exert antiadhesive properties by binding to the urokinase receptor (uPAR) and vitronectin. We de...

Previous studies from this laboratory have implicated the expression of the third isoform of metallothionein (MT-3) in the maintenance of proximal tubular vectorial active ion transport. It was shown that HK-2 cells have no expression of MT-3 and do not form domes in culture; whereas, the human proximal tubular (HPT) cells and HK-2 cells stably transfected with MT-3 [HK-2(MT-3)] form these stru...