BACKGROUND Magnetic Resonance Imaging (MRI) is considered the mainstay imaging investigation in patients suspected of lumbar disc herniations. Both imaging and clinical findings determine the final decision of surgery. The objective of this study was to assess MRI observer variation in patients with sciatica who are potential candidates for lumbar disc surgery. METHODS Patients for this study...

STUDY DESIGN Review and reinterpretation of existing literature. OBJECTIVE To suggest how intervertebral disc degeneration might be distinguished from the physiologic processes of growth, aging, healing, and adaptive remodeling. SUMMARY OF BACKGROUND DATA The research literature concerning disc degeneration is particularly diverse, and there are no accepted definitions to guide biomedical r...

Bilateral optic disc edema in a diabetic patient may be caused by diabetic papillopathy. We herein report on a patient with bilateral optic disc drusen simulating diabetic papillopathy. A 55-year-old patient with type 2 diabetes presented with decreased vision of 1-month. Diabetic papillopathy was initially considered as there was disc edema in both eyes with focal hemorrhages at the disc margi...

Optic disc pit and optic nerve coloboma are examples of congenital optic disc abnormalities. Although optic nerve coloboma can be inherited in an autosomal dominant fashion, no conclusive link has been found in the case of optic disc pit as an autosomal dominant disease. We describe two cases: a daughter with an optic disc pit complicated by maculopathy and her mother with a congenitally abnorm...

Background & Aim: Low back pain is broadly documented as one of the most widespread pathologies in the advanced domain. Although the reasons of low back pain are uncountable, it has been meaningfully related to intervertebral disc degeneration. Present therapies for Intervertebral Disc (IVD) degeneration such as physical therapy and spinal fusion reduce symptoms' severity, but do not treat the ...

purpose: to determine the effect of induced myopia and hyperopia using soft contact lenses on optic disc parameters measured by fourier domain optical coherence tomography (fd-oct) in emmetropic persons. methods: in a quasi-experimental self controlled study, 57 normal emmetropic participants 18-42 years of age were studied. each subject underwent a complete ophthalmic examinations including me...

results the depression and disability scores of patients before lumbar discectomy significantly decreased after surgery. conclusions our results indicate that lumbar discectomy surgery significantly improved depression and disability in patients with chronic herniated discs. patients and methods one hundred forty-eight patients with chronic low back pain and radicular leg pain were included in ...

pomegranate tree possesses a vast ethnomedical history and represents a phytochemical reservoir of heuristic medicinal value. in the present study, total phenolics, antioxidant, and antibacterial activities of pomegranate peel were determined by folin–ciocalteu, 2,2-diphenyl-1-picrylhydrazyl (dpph) and disk-diffusion methods, respectively, and compared among the accessions. methanolic extract g...

Little information is at hand on the diagnostic values of the clinical symptoms and signs in the level diagnosis of patients with lower lumbar disc herniation.  We examined one hundred and thirty nine consecutive candidates for lower lumbar discectomy.  Monoradicular pain with signs attributed to the fifth lumbar and first sacral root dysfunctions were evaluated independently in each patient.  ...