The effect of ethidium bromide (EB) on phytohaemagglutinin (PHA) induced lymphocyte transformation and mitosis was evaluated by morphology and 3H-thymidine uptake. EB at low concentrations is known to specifically bind to mitochondrial DNA and selectively inhibit mitochondrial protein synthesis. However at these concentrations EB inhibited both transformation and mitosis. Electron micrographs o...

It has been proved that kindling model of amygdala is sensitive to estradiol because the latter accelerates the overall rate of kindling. However the effect of estrogen on the seizure process has not been investigated. In this study fully kindled male rats were treated with different doses (10, 30, and 50 µg/kg, i.p.) of estradiol benzoate (EB) daily and such kindling parameters as seizure stag...

| The throughput performance of some multiaccess wireless systems is compared on the basis of the average energy per successfully received information bit Eb=N0. We prove that, for an optimal choice of the system parameters, some systems are not interference limited and have a similar behavior: at high Eb=N0 they \self-orthogonalize", i.e., on the average only one user per degree of freedom is ...

BACKGROUND Inherited epidermolysis bullosa (EB) comprises a highly heterogeneous group of rare diseases characterized by exacerbated skin and/or mucosal fragility and blister formation after minor mechanical trauma. Level of cleavage in the skin, clinical features with immunofluorescence antigen mapping and/or electron microscopy examination of a skin biopsy and/or gene involved, type(s) of mut...

BACKGROUND Inherited epidermolysis bullosa (EB) is a group of skin diseases characterized by blistering of the skin and mucous membranes.There are four major types of EB (EB simplex, junctional EB, dystrophic EB and Kindler syndrome) caused by different gene mutations. Dystrophic EB is derived from mutations in the type VII collagen gene (COL7A1), encoding a protein which is the predominant com...

BACKGROUND To prevent inappropriate empiric antibiotic treatment in patients with bacteremia caused by third-generation cephalosporin (3GC)-resistant Enterobacteriaceae (3GC-R EB), Dutch guidelines recommend β-lactam and aminoglycoside combination therapy or carbapenem monotherapy in patients with prior 3GC-R EB colonization and/or recent cephalosporin or fluoroquinolone usage. Positive predict...

Although the epileptogenic properties of estrogens have been widely demonstrated in several models and species, the mechanism(s) by which estrogens can acutely change seizure parameters including after discharge and seizure durationremains to be determined. In the present study, we examined the role of NMDA (N-methyl-D-aspartate), non-NMDA andestrogen receptors in estradiol benzoate(EB) effects...

Epidermolysis bullosa (EB) is a diverse group of disorders that have as a common feature blister formation with tissue separation occurring at variable depths in the skin and/or mucosa depending on the specific EB type. There may be marked oral involvement, potentially creating devastating alterations in the soft and hard tissues. Oral tissue fragility and blistering is common to all EB types. ...

AIM To assess proliferative and apoptotic potential of the seminiferous epithelium cells in relation to Sertoli cell maturation in newborn rats under the influence of estradiol, follicle stimulating hormone (FSH) or both agents given together. METHODS From postnatal day (PND) 5 to 15 male rats were daily injected with 12.5 microg of 17beta-estradiol benzoate (EB) or 7.5 IU of human purified F...