Background: IL-4 is a cytokine that induces differentiation of naive helper T cells into Th2 cells. Once activated by IL-4, Th2 cells subsequently produce additional IL-4. Objective: To examine the effect of IL-4 on IL-17 production and its effect in Collagen- Induced Arthritis (CIA) mice. Method: In this study, a chicken collagen-II-induced experimental arthritis (CIA) model was used in DBA/1 ...

Automatic performance tuning (auto-tuning) has been used in parallel numerical applications for adapting performance-relevant parameters. We extend auto-tuning to general-purpose parallel applications on multicores. This paper concentrates on Atune-IL, an instrumentation language for specifying a wide range of tunable parameters for a generic auto-tuner. Tunable parameters include the number of...

Interfaces to information retrieval (IR) systems increasingly support progressive interactive search formulation and refinement. Part of their aim is to make information retrieval easier for the end user without the need for (or with minimal support from) an information intermediary. One approach to supporting these activities has been to design ‘intelligent’ interfaces that embody some of the ...

Despite being central to many game stories, dynamic social relationships in video games are difficult to make playable in meaningful ways. To help address this issue, this paper presents the Ensemble Engine (EE), the first publicly available “social physics” engine. The Ensemble Engine is inspired by the lessons learned from more than five years building the Comme il Faut (CiF) social physics e...

RÉSUMÉ. La croissance très importante des informations disponibles sur Internet nécessite des outils de recherche de plus en plus performants permettant de discerner efficacement les informations intéressantes parmi des centaines voire des milliers de documents. Seulement, la qualité des résultats fournis par les moteurs de recherche traditionnels n'est pas toujours pertinente surtout quand il ...