High litter size or twinning is an economically important trait that enhances sheep productivity. The FecXG has been influentially associated with the ovulation rate in various breeds. However, there limited information about this locus Kivircik breed. Therefore, aim of study was to evaluate presence Galway (FecXG) mutation (n=91) raised Kirklareli province. Genomic DNA isolated from whole bloo...

هدف: از چالش­های عمده بشریت افزایش افسردگی و اختلال عملکرد جنسی ناشی داروهای ضدافسردگی است. با توجه به نقش سلول­های سرتولی در اسپرماتوژنز، پژوهش حاضر، اثر داروی دولوکستین را بر زنده­مانی، آپوپتوزیس بیان ژن­های Bax و­ (Connexin 43) Cx43 بررسی کرده مواد روش‌‌ها: TM4 محیط DMEM/F12 حاوی %5/2 FBS، 5% سرم اسب %1 پنی سیلین-استرپتومایسین کشت شدند. دوزهای 30،60، 15، 5/7، 75/3 میکرو­گرم/ میلی­لیتر زمان­ه...

Mammalian oocytes secrete transforming growth factor β (TGF-β) superfamily proteins, such as growth differentiation factor 9 (GDF9), bone morphogenetic protein 6 (BMP6) and BMP15, and fibroblast growth factors (FGFs). These oocyte-derived paracrine factors (ODPFs) play essential roles in regulating the differentiation and function of somatic granulosa cells as well as the development of ovarian...

This study aimed to examine the polymorphism of BMP15 (FecX$^{G}$ and FecX$^{I}$) GDF9 (G1 G4) genes association between genotypes litter size in Akkaraman breed. Blood samples were taken from 100 ewes total. Genomic DNA was obtained whole blood. The PCR-RFLP technique employed determine polymorphisms under investigation. G1 only polymorphic among four loci analyzed. frequencies for GA GG 0.26 ...