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OBJECTIVES/HYPOTHESIS To examine the relationship between cerebrospinal fluid (CSF) rhinorrhea and obstructive sleep apnea (OSA). STUDY DESIGN Retrospective chart review of patients who underwent surgical repair of encephaloceles and/or CSF rhinorrhea at a tertiary medical center over a 12-year period. METHODS Pertinent demographic, clinical, and surgical data including age, sex, and medica...
The purpose of this study was to explore the relationship between sleep apnea indicators and injury in older farmers from Kentucky and South Carolina. Participants reported at least 1 day of farm work during the preceding year (n = 756) and received income from farming. The primary outcome variable was occurrence of injuries because of farm work in the past year. Main explanatory variables of i...
IPAM GBM Tutorials March 27 – April 6 , 2001 Level Set Methods : An Overview and Some Recent Results
The level set method was devised by Osher and Sethian in [64] as a simple and versatile method for computing and analyzing the motion of an interface Γ in two or three dimensions. Γ bounds a (possibly multiply connected) region Ω. The goal is to compute and analyze the subsequent motion of Γ under a velocity field v. This velocity can depend on position, time, the geometry of the interface and ...
Schizophrenia is a mental disorder characterized by impairments in behavior, thought, and neurocognitive performance. We searched for susceptibility loci at a quantitative trait locus (QTL) previously reported for abstraction and mental flexibility (ABF), a cognitive function often compromised in schizophrenia patients and their unaffected relatives. Exome sequences were determined for 134 samp...
BACKGROUND Myxomatous mitral valve disease (MMVD) is an important cause of morbidity and mortality in dogs. OBJECTIVES To compare, throughout the period of follow-up of dogs that had not yet reached the primary endpoint, the longitudinal effects of pimobendan versus benazepril hydrochloride treatment on quality-of-life (QoL) variables, concomitant congestive heart failure (CHF) treatment, and...
OBJECTIVES Alarm over the reported high failure rates for metal-on-metal (MoM) hip implants as well as their potential for locally aggressive Adverse Reactions to Metal Debris (ARMDs) has prompted government agencies, internationally, to recommend the monitoring of patients with MoM hip implants. Some have advised that a blood ion level >7 µg/L indicates potential for ARMDs. We report a systema...
BACKGROUND AND OBJECTIVES Laparoscopic adjustable gastric banding is an effective and popular bariatric surgery for weight loss in obese patients that traditionally involves up to 5 incisions. Recently, a more minimally invasive single-incision technique has been developed. In this retrospective study, we compare conventional and single-incision laparoscopic adjustable gastric banding with rega...
OBJECTIVES/HYPOTHESIS The primary objective was to determine if sleep study variables (e.g., apnea-hypopnea index [AHI] and lowest oxygen saturation) and quantitative sleepiness data improve following isolated hyoid surgery for obstructive sleep apnea (OSA). STUDY DESIGN Systematic review and meta-analysis. METHODS Nine databases, including PubMed, were searched through September 5, 2015. ...
BACKGROUND Limited options are available for the treatment of pain in cats. Monoclonal antibodies (mAbs) that neutralize nerve growth factor (NGF) have demonstrated analgesic capacity in rodent models, people with osteoarthritis, and dogs with degenerative joint disease. HYPOTHESIS/OBJECTIVES This study describes the design and characterization of a fully felinized anti-NGF monoclonal antibod...
We study the long time evolution of a quantum particle interacting with a random potential in the Boltzmann-Grad low density limit. We prove that the phase space density of the quantum evolution defined through the Husimi function converges weakly to a linear Boltzmann equation. The Boltzmann collision kernel is given by the full quantum scattering cross section of the obstacle potential. 1 The...
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