A large class of dynamic systems can be decomposed into or approximated by cascaded subsystems. Applications include multi-agent systems, distributed process control, and hierarchical large-scale systems. Nonlinear dynamic systems can be represented as Takagi-Sugeno (TS) fuzzy models, with linear or affine consequents. For cascaded TS systems, it has been proven that the stability of the subsys...

Introduction Familial Mediterranean Fever (FMF) is considered a rare disease in Japan. Our institution began screening for MEFV gene mutations in patients with periodic fever in 2005. Among the 18 patients screened, we have identified 11 (56.5%) FMF patients with heterozygous M694I/E148Q mutations. Among the other 7 patients, no pathogenic mutations were detected by the direct sequencing of all...

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We present a study of two X-ray bursters in the Galactic Center field with the ART-P telescope onboard GRANAT. During 1990-1992 approximately 100 X-ray bursts were detected from the Galactic Center field and most of them were identified with the two persistent sources, A1742-294 and SLX1744-299/300. The burst recurrence times were found to be ∼ 2.4 and ∼ 4.6 hours, respectively, which is signif...

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Standoff detection measuring the fluorescence spectra of seven different biological agents excited by 294 nm as well as 355 nm wavelength laser pulses has been undertaken. The biological warfare agent simulants were released in a semi-closed aerosol chamber at 210 m standoff distance and excited by light at either of the two wavelengths using the same instrument. Significant differences in seve...

The arenavirus envelope glycoprotein (GPC) mediates viral entry through pH-induced membrane fusion in the endosome. This crucial process in the viral life cycle can be specifically inhibited in the New World arenaviruses by the small-molecule compound ST-294. Here, we show that ST-294 interferes with GPC-mediated membrane fusion by targeting the interaction of the G2 fusion subunit with the sta...