Immunosuppression is an essential aspect of managing cardiac sarcoidosis (CS). The decision to implant a cardiovascular implantable electronic device (CIED) often made in conjunction with starting immunosuppression. It unclear if immunosuppression at the time implantation increases risk CIED infections. Since both are potentially life-saving therapies for CS, it vital understand there need adju...

IgA vasculitis (IgAV) is a systemic, immune complex–mediated, small-vessel leukocytoclastic vasculitis. In the cutaneous tissue, it characterized by nonthrombocytopenic palpable purpura. Increasing evidence suggests importance of host immunity in its contribution to IgAV. However, molecular mechanisms tissue damage IgAV remain largely unknown. We performed single-cell RNA sequencing on biopsied...

Abstract Study question To evaluate an automated sperm morphology assessment method using the KNIME Analytics Platform compared to manual analysis performed as per WHO guidelines. Summary answer Our emphasizes how artificial intelligence technologies have potential foster standardization of with comparable precision and reliability. What is known already Manual considered most difficult paramet...

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survival in patients with HCC in two independent cohorts, and the mechanism was associated with low VEGFR-1 expression levels in HCC. Grant support: This research was supported by grants from the National Scientific Council (NSC 100-2314-B-075-051, NSC 101-2321-B075-004) and Taipei Veterans General Hospital (V101B-005, V102E2005 and V102E2-006) to YF Hu, (NSC99-3112-B-010-005-CC1, NSC1002627-B-...

Accepted by The Astrophysical Journal Received ; accepted – 2 – ABSTRACT We present a high-energy study of the intriguing COS–B γ-ray field, 2CG 075+00, in order to search for possible counterparts. New EGRET data show that the COS–B emission probably corresponds to two localized γ-ray sources, 3EG J2016+3657 and 3EG J2021+3716. Spectral fits to these EGRET sources, assuming a power-law model, ...

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