BACKGROUND PCR has evolved into one of the most promising tools for T. cruzi detection in the diagnosis and control of Chagas disease. However, general use of the technique is hampered by its complexity and the lack of standardization. METHODOLOGY We here present the development and phase I evaluation of the T. cruzi OligoC-TesT, a simple and standardized dipstick format for detection of PCR ...

Photoplethysmography (PPG) devices are widely used for monitoring cardiovascular function. However, these devices require skin contact, which restricts their use to at-rest short-term monitoring. Photoplethysmographic imaging (PPGI) has been recently proposed as a non-contact monitoring alternative by measuring blood pulse signals across a spatial region of interest. Existing systems operate in...

The Data Availability Statement appearing with the published article is incorrect. The correct Data Availability Statement should read: There are legal restrictions on the student outcome data. National Child Measurement Programme data was used as determined by the data sharing agreement with the then Information Centre of the National Health Service (NHS IC), now Health and Social Care Informa...

CONTEXT Screening for lead poisoning is necessary in young children, but obtaining the needed blood sample is unpleasant and sometimes very difficult. Use of an alternative screening method that is less unpleasant and less difficult would likely help to increase the percent of children receiving screening. OBJECTIVES To evaluate the correlation of oral fluid and blood lead in a clinical setti...

background and objectives: leptospirosis is an important zoonotic disease caused by leptospira interrogans . leptospirosis leads to economical losses in dairy farm industry. the objective of this study was to evaluate the pathogenic serovars of leptospira interrogans in dairy cattle herds of shahrekord by pcr. materials and methods: two hundred samples (100 urine and 100 blood) were collected f...

With a novel real-time multiplex polymerase chain reaction test, the LightCycler SeptiFast® test, 25 bacterial and fungal species can be identified directly in blood. The SeptiFast® test has been used for rapid etiologic diagnosis in infectious endocarditis using blood samples but has not been evaluated directly on cardiac vegetations in patients being treated for infectious endocarditis. We pr...

OBJECTIVE To evaluate the effect of apheresis procedure on platelet's activation dependent glycoproteins' expression on their surface. METHODS This study was conducted between June 2012 and June 2014, and comprised blood and platelet samples. Two samples were collected i.e. venous blood sample and apheresed platelet sample from the same donor. Platelet cluster of differentiation markers (41, ...

Molecular weight distribution of prion proteins in meat, blood, processed blood products, gelatin, milk, cheese has been studied in a paper. The obtained electrophoregrams of blood plasma samples indicate the presence of two fractions of blood protein in the range of 30 to 40 kDa. The relative abundance of these proteins in the blood plasma contains 22.06 % of the total, which are 2.15 g/100 g ...

OBJECTIVE To investigate pre-analytical variables and the diagnostic performance of the platelet function analyser (PFA-100), a new device to test primary haemostasis in vitro by simulating platelet adhesion and aggregation under high shear stress. METHODS Venous whole citrated blood is aspirated through a capillary towards an aperture of a collagen coated membrane containing either adenosine...

BACKGROUND Assays to screen for and confirm the presence of the antibody for human T-lymphotropic virus type I (HTLV-I) are currently performed with serum or plasma. We developed and evaluated a new counting immunoassay (CIA) for the detection of HTLV-I antibody in whole blood, using recombinant and synthetic peptide antigens. METHODS We assessed the CIA for detection of HTLV-I antibody in wh...