O presente artigo está relacionado a nova regra etária para concessão do benefício de aposentadoria especial acordo com reforma previdenciária. Tem como objetivo analisar aplicabilidade inciso I, alíneas a, b e c 19 da Emenda Constitucional 103/19 os motivos que tornam esse dispositivo inconstitucional bem demonstrar fundamentos expostos na Ação Direta Inconstitucionalidade 6.309 corroboram tem...

A variant form of an Anopheles dirus glutathione S-transferase (GST), designated AdGSTD4-4, possesses a single amino acid change of leucine to arginine (Leu-103-Arg). Although residue 103 is outside of the active site, it has major effects on enzymic properties. To investigate these structural effects, site-directed mutagenesis was used to generate mutants by changing the non-polar leucine to a...

Objectives Recent studies revealed that microRNAs (miRNAs) may play crucial roles in the responses and pathologic processes of spinal cord injury (SCI). This study aimed to investigate the effect and the molecular basis of miR-103 on LPS-induced injuries in PC12 cells in vitro and SCI rats in vivo. Materials and Methods PC12 cells were exposed to LPS to induce cell injuries to mimic the in vi...

Amoebae of Naegleria gruberi were cytopathic for cultures of rat neuroblastoma (B-103) cells. N. gruberi grew and destroyed B-103 cells at 30 degrees C. As few as one amoeba inoculated per million B-103 cells resulted in cytopathogenicity after extensive growth of N. gruberi.