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UNLABELLED Semen enhances HIV infection in vitro, but how long it retains this activity has not been carefully examined. Immediately postejaculation, semen exists as a semisolid coagulum, which then converts to a more liquid form in a process termed liquefaction. We demonstrate that early during liquefaction, semen exhibits maximal HIV-enhancing activity that gradually declines upon further inc...
در حالیکه معمولا گفته می شود که دولت اوباما فاقد هرگونه استراتژی در سیاست خار...
....................................................................................... 88 Introduction ..................................................................................... 89 Methods........................................................................................ 92 Results & Discussion......................................................................... 99 Acknowle...
Previous studies in Parkinsonian rats and monkeys have shown that b2-selective nicotinic acetylcholine receptor (nAChR) agonists reduce L-Dopa–induced dyskinesias (LIDs), a serious complication of L-Dopa therapy for Parkinson’s disease. Since rodent studies also suggested an involvement of a7 nAChRs in LIDs, we tested the effect of the potent, selective a7 agonist ABT-107 [5-(6-[(3R)-1-azabicyc...
A/A test, 67. See also online bucket tests A/B test, 8, 55. See also online bucket tests accuracy metrics, 59–62, 63 adaptive sequential design. See multiarmed bandit (MAB) problem Adomavicius, Gediminas, 261 Agarwal, Deepak K., 97, 99, 107, 110, 147, 198, 210, 242, 250t, 251, 252, 253, 261 algorithmic techniques, for recommender system, 5–7 alternating least squares, 35 AOL, 82t application se...
Nicotinic acetylcholine receptor (nAChR) agonists improve sensory gating deficits in animal models and schizophrenic patients. The aim of this study was to determine whether the novel and selective α7 nAChR full agonist 5-(6-[(3R)-1-azabicyclo[2.2.2]oct-3-yloxy]pyridazin-3-yl)-1H-indole (ABT-107) improves sensory gating deficits in DBA/2 mice. Sensory gating was measured by recording hippocampa...
Previous studies in Parkinsonian rats and monkeys have shown that β2-selective nicotinic acetylcholine receptor (nAChR) agonists reduce l-Dopa-induced dyskinesias (LIDs), a serious complication of l-Dopa therapy for Parkinson's disease. Since rodent studies also suggested an involvement of α7 nAChRs in LIDs, we tested the effect of the potent, selective α7 agonist ABT-107 [5-(6-[(3R)-1-azabicyc...
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