PURPOSE The transcriptional regulation of the human reduced folate carrier (hRFC), involved in cellular uptake of methotrexate and reduced folates, was studied in childhood acute lymphoblastic leukemia (ALL). The hRFC gene is regulated by six noncoding exons (A1/A2 and A to E) and multiple promoters. In ALL, hRFC-A1/A2 and hRFC-B are the major transcript forms. EXPERIMENTAL DESIGN RNAs from 1...

Aim: The purpose of this study was to determine retrospectively, clinically and radiographically the success rate of single–visit root canal treatment and determine the possible factors that could affected there prognosis.Materials and Methods: nine–hundred and sixty–five single–visi1 cases, of which 322 present for re–examination appointment ranging from 6 months to 5 years from the day of tre...

OBJECTIVE To study the effect of using smokeless tobacco during pregnancy on babies' birth weight and gestational age at birth. DESIGN Population based, prospective cohort study using a house to house approach. SETTING Eight primary health post areas in the city of Mumbai (Bombay), India. PARTICIPANTS 1217 women who were three to seven months pregnant and planning to deliver in the study ...

OBJECTIVE To determine the 25-hydroxyvitamin D (25[OH]D) serum levels in refugee women of childbearing age and in refugee children; to compare their 25(OH)D levels with the recommended levels in order to determine the prevalence of deficiency; to compare their 25(OH)D levels with those in the general Canadian population in the appropriate age and sex groups; and to investigate the association o...

Una propuesta eficiente, para disminuir los niveles desodio en productos cárnicos y desarrollar formulacionessaludables, es la cantidad de cloruro sodio (NaCl) mediante sustitución por que no alteren las características proximales sensoriales. El principal objetivo esta investigación fue evaluar parcial NaCl KCl su efecto elaboración salchicha pollo. La evaluación (pH, humedad, grasa proteína) ...

We analyze the response and thermal behavior of an Unruh-DeWitt detector as it travels through cosmological spacetimes, with special reference to question how define surface gravity temperature in dynamical spacetimes. Working within quantum field theory on curved spacetime approximation, we consider a along geodesic accelerated Kodama trajectories de Sitter asymptotically FLRW By modelling usi...