BACKGROUND/AIMS Epithelial-to-mesenchymal transition (EMT) in cancers is related to metastasis, recurrence, and poor prognosis. We evaluated whether EMT-related proteins can act as prognostic biomarkers in colorectal cancer (CRC) patients. METHODS We evaluated the expression of E-cadherin, β-catenin, and S100A4 by immunohistochemistry (IHC) in 333 CRC tissues from the tumor center and invasiv...

Introduction: The significance of tumor budding and programmed death ligand 1 (PD-L1) has not been established in gastric adenocarcinoma (GAC). Objectives: This study evaluated PD-L1 expression with regard to microenvironment, clinicopathologic parameters, overall survival GAC. Patients Methods: Totally, 102 GAC cases were assessed immunohistochemically. associations features, tumor-infiltratin...

Background: Male reproductive disorders that are of interest from an environmental point of view include sexual dysfunction, infertility, cryptorchidism, hypospadias and testicular cancer. Several reports suggest declining sperm counts and increase of these reproductive disorders in some areas during some time periods past 50 years. Materials and Methods: Except for testicular cancer this evide...

We have used correlated scanning EM (SEM) and multiphoton fluorescence microscopy to visualize budding of virus-like particles (VLPs) of Rous sarcoma virus (RSV) and HIV type 1 (HIV-1). When the Gag structural protein was expressed alone as a GFP fusion, most budding particles appeared morphologically aberrant, but normal assembly could be rescued by coexpression of untagged Gag protein. Imagin...

ing proteins assembles at the site marked by the cue, *Department of Molecular and Cell Biology then a polarized actin and septin cytoskeleton assemUniversity of California, Berkeley bles, and the secretory apparatus becomes oriented Berkeley, California 94720 toward the spatial cue. Considerable information about †Department of Molecular and Cellular Physiology bud formation has been obtained ...

Abstract Background The world today is faced with the humongous challenge of removing numerous plastic wastes in our environment. Efforts removal or remediation these materials from ecosystem are presently at budding stage. Some researchers have shown that certain bacterial enzymes ability to hydrolyze and further degrade compounds. In this study, PET hydrolase enzyme polyvinylchloride, polyure...

Male sexual aggregations are a common territorial, mating-related or resource-based, behaviour observed in diverse organisms, including insects such as thrips. The influence of factors such as plant substrate, time of day, and geographic location on aggregation of thrips is uncertain, therefore we monitored the dispersion of male and female bean flower thrips (BFT), Megalurothrips sjostedti (Tr...

in order to determine the effects of water deficit at different growth stages of sugar beet and optimal usage of water on quality and quantity characters of sugar beet, a factorial experiment based on randomized complete block design was conducted with 13 treatments and four replications in 2000 and 2001 in agricultural research center of hamadan. for the first factor, irrigation withheld in th...