Trypsin was immobilized on linolenic acid modified chitosan using glutaraldehyde (GA) as cross-linker, which was confirmed by Fourier transform infrared (FTIR) spectra. The chitosan nanoparticles containing trypsin (TR) can be prepared after the sonication of immobilized trypsin. The GA concentration affected both the enzyme activity of the nanoparticle and particle size. Results indicated that...

BACKGROUND This study was to determine common methods to treat addiction used by patients checked into Outpatient Treatment and Rehabilitation Clinics in Tehran. METHODS The study was conducted in Social Security affiliated outpatient clinics including three governmental and several private centers in 22 districts of Tehran. Demographic data, personal information, social characteristics and i...

Severe acetaminophen hepatotoxicity frequently leads to acute liver failure (ALF). We determined the incidence, risk factors, and outcomes of acetaminophen-induced ALF at 22 tertiary care centers in the United States. Detailed prospective data were gathered on 662 consecutive patients over a 6-year period fulfilling standard criteria for ALF (coagulopathy and encephalopathy), from which 275 (42...

We observed PSR J0437−4715 with the FUV-MAMA detector of the Hubble Space Telescope Imaging Spectrometer (STIS) to measure the pulsar’s spectrum and pulsations. For the first time, UV emission from a millisecond pulsar is detected. The measured flux, (2.0± 0.2)× 10 erg s cm in the 1150–1700 Å range, corresponds to the luminosity LFUV = (4.7 ± 0.5) × 10 27 erg s, for the distance of 140 pc and n...

[PDF] [Full Text] [Abstract] , August , 2011; 111 (2): 358-366. J Appl Physiol D. G. Allen, E. Clugston, Y. Petersen, I. V. Röder, B. Chapman and R. Rudolf fatigue Interactions between intracellular calcium and phosphate in intact mouse muscle during [PDF] [Full Text] [Abstract] , November , 2011; 111 (5): 1372-1379. J Appl Physiol Magni Mohr, Jens Jung Nielsen and Jens Bangsbo interstitial...

The aim of this study was to evaluate the utility of hemoglobin A1c (HbA1c) to identify individuals with diabetes and prediabetes in the Japanese population. A total of 1372 individuals without known diabetes were selected for this study. A 75 g oral glucose tolerance test (OGTT) was used to diagnose diabetes and prediabetes. The ability of HbA1c to detect diabetes and prediabetes was investiga...

BACKGROUND Endothelial cell dysfunction, by promoting fibrin deposition, has been implicated in the development of multiple organ failure. Altered fibrinolysis during inflammation may participate in microvascular alterations. We sought to determine whether plasma fibrinolysis was related to the severity of organ dysfunction and/or to the levels of von Willebrand factor (vWF antigen), as a marke...

We show that if four suitable matrices of order m exist then there are Hadamard matrices of order 28 m, 36 m, and 44 m. In particular we show that Hadamard matrices of orders 14(q + 1), 18(q + 1), and 22(q + 1) exist when q is a prime power and q = l(mod 4). Also we show that if n is the order of a conference matrix there is an Hadamard matrix of order 4mn. As a consequence there are Hadamard m...

This prospective multicenter study evaluated separately the significance of maternal injection drug use (IDU) and human immunodeficiency virus type 1 (HIV-1) coinfection in vertical transmission of hepatitis C virus (HCV). In all, 1372 consecutive, unselected HCV antibody-positive mothers and their infants were studied. Maternal HIV-1 coinfection (crude odds ratios [OR], 1.41; 95% confidence in...

Eggpant (Solanum melongena L.) that are common in Indonesia are already known contain anthocyanins as antioxidants as well as a-glukosidase inhibitor that can inhibit the rise of blood glucose in diabetes mellitus (DM). This study aimed to determine that the eggplant extract has antihyperglicemic effect and the effective dose as well. This was an experimental study with post test only control g...