نتایج جستجو برای: 16 apr
تعداد نتایج: 336617 فیلتر نتایج به سال:
OBJECTIVES Conduct a feasibility study on the effect of menstrual hygiene on schoolgirls' school and health (reproductive/sexual) outcomes. DESIGN 3-arm single-site open cluster randomised controlled pilot study. SETTING 30 primary schools in rural western Kenya, within a Health and Demographic Surveillance System. PARTICIPANTS Primary schoolgirls 14-16 years, experienced 3 menses, no pre...
BACKGROUND Understanding co-morbidity of depression and tuberculosis (TB) has been limited by challenges in measurement of depression due to overlapping symptoms, use of small hospital samples and uncontrolled analysis. This study was conducted to better understand the burden and presentation of depression, and associated factors in people with TB in primary care settings in Ethiopia. METHODS...
BACKGROUND Bladder exstrophy (BE) and cloacal exstrophy (CE) are rare birth defects that have been reported to occur in 1:30,000-50,000 and 1:200,000-400,000 live births. Disagreement exists as to whether they comprise two distinct disorders or are part of a spectrum. We examined epidemiologic trends and risk factors for BE and CE in a large population-based dataset. METHODS Potential cases w...
INTRODUCTION Alcohol use by persons living with HIV/AIDS (PLWHA) negatively impacts the public health benefits of antiretroviral therapy (ART). Using a standardized alcohol assessment tool, we estimate the prevalence of alcohol use, identify associated factors, and test the association of alcohol misuse with sexual risk behaviors among PLWHA in Uganda. METHODS A cross-section of PLWHA in Kamp...
BACKGROUND Arthroscopic patellar release (APR) is utilized for minimally invasive surgical treatment of patellar tendinopathy. Evidence regarding long-term success following the procedure is limited. Also, the influence of age and preoperative performance level, are incompletely understood. The aim of this study was to investigate whether APR translates into sustained pain relief over a long-te...
BACKGROUND Mutation in the tumor suppressor gene TP53 is an early event in the development of high-grade serous (HGS) ovarian cancer and is identified in more than 96 % of HGS cancer patients. APR-246 (PRIMA-1(MET)) is the first clinical-stage compound that reactivates mutant p53 protein by refolding it to wild type conformation, thus inducing apoptosis. APR-246 has been tested as monotherapy i...
Editor's note: Increasingly, quality improvement initiatives emphasize public reporting of hospital performance measures, to encourage providers to improve, to help consumers pick providers, and to determine provider payments. Although these measures are based on compliance with well-established processes of care, it is unknown whether quality measured in this way is correlated with, or predict...
Most people sooner or later experience dilemmas or uncertainties involving questions of meaning, purpose, value, and fulfillment. Such questions emerge in the context of relationships, career, momentous change, personal responsibility, aspiration or disappointment, and decision-making under risk or potential conflict of interest. Normal problems of living are not regarded as “diseases”; rather,...
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