BACKGROUND Prostaglandins of the E series and misoprostol (a stable analogue of prostaglandin E(1)) prevent bronchoconstriction following aspirin ingestion or inhalation in subjects with aspirin sensitive asthma. A study was undertaken to investigate the influence of misoprostol on the course of aspirin induced asthma. METHODS A double blind, crossover, randomised, placebo controlled study wa...

Three hundred one-day-old male broilers (Ross 308) were allocated to five treatments with four replicates in a completely randomized design. Treatments supplemented with 0 (control), 400, 800, 1200 or 1600 ppb chromium in the form of chromium chloride. All birds were intramuscularly immunized with killed vaccine of Newcastle and Avian Influenza (H9 N2) virus at 8 d. On days 18 and 28 blood samp...

BACKGROUND & OBJECTIVES Various materials have been used as scaffolds to suit different demands in tissue engineering. One of the most important criteria is that the scaffold must be biocompatible. This study was carried out to investigate the potential of HA or TCP/HA scaffold seeded with osteogenic induced sheep marrow cells (SMCs) for bone tissue engineering. METHODS HA-SMC and TCP/HA-SMC ...

Influenza viruses routinely acquire mutations in antigenic sites on the globular head of the hemagglutinin (HA) protein. Since these antigenic sites are near the receptor binding pocket of HA, many antigenic mutations simultaneously alter the receptor binding properties of HA. We previously reported that a K165E mutation in the Sa antigenic site of A/Puerto Rico/8/34 (PR8) HA is associated with...

Interrelations exist in the terrestrial ecosystems between the plant type and characteristics of nutrient uptake. Annual net nitrogen mineralization in soils of different plant communities in the high altitude zone of Spil mountain located in the Mediterranean phytogeographical region of Turkey was investigated throughout one year by field incubation method. Seasonal fluctuations resulting from...

Murine anti-CD3 (OKT3, Muromonab-CD3) is a potent human T-lymphocyte mitogen. A previous clinical Phase I trial examined OKT3 as an immunomodulator for the treatment of cancer. However, the murine monoclonal antibody triggered a potent humoral response that neutralized the antibody activity during subsequent administration. Thus, a "humanized" form of OKT3 (hOKT3gamma4) was developed to minimiz...

The occurrence of a weak auditory warning stimulus increases the speed of the response to a subsequent visual target stimulus that must be identified. This facilitatory effect has been attributed to the temporal expectancy automatically induced by the warning stimulus. It has not been determined whether this results from a modulation of the stimulus identification process, the response selectio...