10 One central goal of genome biology is to understand how the usage of the genome differs between 11 organisms. Our knowledge of genome composition, needed for downstream inferences, is critically 12 dependent on gene annotations, yet problems associated with gene annotation and assembly errors are 13 usually ignored in comparative genomics. Here we analyze the genomes of 68 species across all...

To test adrenal responsiveness of beef cattle to stress, plasma norepinephrine, epinephrine, and cortisol responses of Angus x Hereford cattle to weaning were measured in blood samples taken from 1) eight cows and their 4- to 6-mo-old calves before and after separation and, the following day, before and after being reunited and 2) an equal number of control animals. After separation and before ...

The recent COVID-19 pandemic has once again caught the attention of people on probable zoonotic transmission from animals to humans, but role companion in coronavirus (CoV) epidemiology still remains unknown. present study was aimed investigate and molecular characterizations CoVs Chengdu city, Southwest China. 523 clinical samples 393 were collected one veterinary hospital between 2020 2021, p...

BACKGROUND Many human epidemiologic studies demonstrate that maternal asthma confers greater risk of asthma to offspring than does paternal disease. However, a handful have shown the opposite. Given this disparity, a meta-analysis is necessary to determine the veracity and magnitude of the "maternal effect." METHODOLOGY/PRINCIPAL FINDINGS We screened the medical literature from 1966 to 2009 a...

We report on the characterization and target analysis of the small (s)RNA(162) in the methanoarchaeon Methanosarcina mazei. Using a combination of genetic approaches, transcriptome analysis and computational predictions, the bicistronic MM2441-MM2440 mRNA encoding the transcription factor MM2441 and a protein of unknown function was identified as a potential target of this sRNA, which due to pr...

We have constructed mouse A9 hybrids containing a single normal human chromosome 15, via microcell-mediated chromosome transfer. Cytogenetic and DNA-polymorphic analyses identified mouse A9 hybrids that contained either a paternal or maternal human chromosome 15. Paternal specific expression of the known imprinted genes SNRPN (small nuclear ribonucleoprotein-associated polypeptide N gene) and I...

The aim of this study is to identify QTL associated with levels of natural antibodies in two population of laying hens. One experimental (H/L) F2 population originates from a cross (ISA Warren) between two divergently selected lines for either high (H line) or low (L line) primary antibody response to sheep red blood cells (SRBC) at 5 weeks of age. Another experimental (F/P) F2 population was c...

isovanillin and iso-acetovanillon are two phenolic components isolated from a number of plants including pycnocycla spinosa . p. spinosa extract has antispasmodic and antidiarrheal activities. however, no comparative study has been done on antidiarrheal action of isovanillin and iso- acetovanillon, so far. the aim of this study was to investigate antidiarrheal action of isovanillin and iso-acet...

Understanding the genetic basis of speciation is a central problem in evolutionary biology. Studies of reproductive isolation have provided several insights into the genetic causes of speciation, especially in taxa that lend themselves to detailed genetic scrutiny. Reproductive barriers have usually been divided into those that occur before zygote formation (prezygotic) and after (postzygotic),...