Purpose: This study aimed to understand the prognostic value of integrin b1 expression in head andneck squamous cell carcinoma (HNSCC) and themechanismunderlying its associationwithmetastatic HNSCC. Experimental Design: Archival HNSCC tissues including 99 nonmetastatic primary tumors and 101 metastatic primary tumors were examined for the association of integrin b1 expression with metastasis an...

AMA Toczek-Wasiak A, Wasiak W, Dzierżanowski T. Advance care planning. Medycyna Paliatywna/Palliative Medicine. 2022;14(4):168-172. doi:10.5114/pm.2022.127032. APA Toczek-Wasiak, A., Wasiak, W., & Dzierżanowski, (2022). Medicine, 14(4), 168-172. https://doi.org/10.5114/pm.2022.127032 Chicago Agnieszka, Wojciech and Tomasz Dzierżanowski. 2022. "Advance planning". Medicine 14 (4): Harvard pp.168-...

B1 cells produce most natural Abs in unimmunized mice and play a key role in the response to thymus-independent Ags and microbial infection. Enlargement of B1 cell number in mice is often associated with autoimmunity. However, the factors that control peripheral B1 cell survival remain poorly characterized. Mice lacking the inhibitory receptor FcγRIIb exhibit a massive expansion in peritoneal B...

The aim of the study described here was to clarify diagnostic value fluttering sign, a new sign that characterizes hepatic hemangiomas in gray-scale ultrasonography (US). It refers phenomenon which speckled echogenicity inside hemangioma changes continuously and seems be moving. A total 172 diagnosed with contrast-enhanced US were evaluated. found 123 (71.5%). Its prevalence significantly highe...

A brief review of the available experimental and theoretical results on production $\chi_{Q1}$ states in $e^+e^-$ annihilation photon-photon $\gamma\gamma^*$ interactions is presented. Future data $\chi_{c1}(1P)$, $\chi_{c1}(3872)$, $\chi_{c1} (4140)$, $\chi_{c1}(4274)$, $\chi_{c1}(4685)$, $\chi_{b1} (1P)$, $\chi_{b1}(2P )$, $\chi_{b1}(3P)$ resonances will help development unification predictio...

The present study reports molecular dynamics simulations for biphasic systems comprising tributyl phosphate (TBP) in dodecane and uranyl nitrate in the aqueous phase, which are key chemical species in the well-known Pu-U extraction (PUREX) process. An attempt has been made to understand the nature of interface and mechanism of 'TBP associated uranyl' crossing under neutral and acidic conditions...

Essentially all nuclear eukaryotic gene transcription depends upon the function of the transcription factor TATA-binding protein (TBP). Here we show that the abundant, multifunctional DNA binding transcription factor repressor activator protein Rap1p interacts directly with TBP. TBP-Rap1p binding occurs efficiently in vivo at physiological expression levels, and in vitro analyses confirm that t...

Transcriptional activity of the TATA-binding protein (TBP) is controlled by a variety of proteins. The BTAF1 protein (formerly known as TAF(II)170/TAF-172 and the human ortholog of Saccharomyces cerevisiae Mot1p) and the NC2 complex composed of NC2alpha (DRAP1) and NC2beta (Dr1) are able to bind to TBP directly and regulate RNA polymerase II transcription both positively and negatively. Here, w...

Sections 4 and 5 are " bonus " material, not part of the syllabus. These notes do not include the proof of PSPACE-completeness of the TQBF problem, which is well explained in Sipser's book. The problem called PATH in Siper's book is called STCONN here. L.T. A machine solves a problem using space s(·) if, for every input x, the machine outputs the correct answer and uses only the first s(|x|) ce...

We have seen that the Fourier transform is well-behaved in the framework of Schwartz functions as well as L, while L is much more awkward. Tempered distributions, which include L, provide a larger framework in which the Fourier transform is well-behaved, and they provide the additional benefit that one can differentiate them arbitrarily many times! To see how this is built up, we start with a r...