نتایج جستجو برای: 18f choline

تعداد نتایج: 26365  

2016
Danny L. Costantini Reza Vali Susan McQuattie Jeffrey Chan Angela Punnett Shiela Weitzman Amer Shammas Martin Charron

We performed an observational pilot study of 18F-FLT PET/CT in pediatric lymphoma. Eight patients with equivocal 18F-FDG PET/CT underwent imaging with 18F-FLT PET/CT. No immediate adverse reactions to 18F-FLT were observed. Compared to 18F-FDG, 18F-FLT uptake was significantly higher in bone marrow and liver (18F-FLT SUV 8.6 ± 0.6 and 5.0 ± 0.3, versus 18F-FDG SUV 1.9 ± 0.1 and 3.4 ± 0.7, resp....

2014
Weiwei Cheng Zhenyu Wu Sheng Liang Hongliang Fu Shuqi Wu Yiyun Tang Zhiyi Ye Hui Wang

UNLABELLED A widespread application of integrin αvβ3 imaging has been emerging in both pre-clinical and clinical studies. But few studies reported its value as compared with 18F-FDG PET, especially for differentiated thyroid cancer (DTC). In this study, we compared the tracer uptake of 18F-AIF-NOTA-PRGD2 and 18F-FDG in lymph node metastasis of DTC to evaluate 18F-AIF-NOTA-PRGD2 as compared with...

Journal: :PloS one 2016
Erik S Mittra Norman Koglin Camila Mosci Meena Kumar Aileen Hoehne Khun Visith Keu Andrei H Iagaru Andre Mueller Mathias Berndt Santiago Bullich Matthias Friebe Heribert Schmitt-Willich Volker Gekeler Lüder M Fels Claudia Bacher-Stier Dae Hyuk Moon Frederick T Chin Andrew W Stephens Ludger M Dinkelborg Sanjiv S Gambhir

PURPOSE (S)-4-(3-[18F]Fluoropropyl)-L-glutamic acid (18F-FSPG) is a novel radiopharmaceutical for Positron Emission Tomography (PET) imaging. It is a glutamate analogue that can be used to measure xC- transporter activity. This study was performed to assess the feasibility of 18F-FSPG for imaging orthotopic brain tumors in small animals and the translation of this approach in human subjects wit...

2016
Julie Bolcaen Kelly Lybaert Lieselotte Moerman Benedicte Descamps Karel Deblaere Tom Boterberg Jean-Pierre Kalala Caroline Van den Broecke Filip De Vos Christian Vanhove Ingeborg Goethals

BACKGROUND Discrimination between glioblastoma (GB) and radiation necrosis (RN) post-irradiation remains challenging but has a large impact on further treatment and prognosis. In this study, the uptake mechanisms of 18F-fluorodeoxyglucose (18F-FDG), 18F-fluoroethyltyrosine (18F-FET) and 18F-fluoromethylcholine (18F-FCho) positron emission tomography (PET) tracers were investigated in a F98 GB a...

2017
Mark G. MacAskill Adriana S. Tavares Junxi Wu Christophe Lucatelli Joanne C. Mountford Andrew H. Baker David E. Newby Patrick W. F. Hadoke

Assessing the retention of cell therapies following implantation is vital and often achieved by labelling cells with 2'-[18F]-fluoro-2'-deoxy-D-glucose (18F-FDG). However, this approach is limited by local retention of cell-effluxed radiotracer. Here, in a preclinical model of critical limb ischemia, we assessed a novel method of cell tracking using 3'-deoxy-3'-L-[18F]-fluorothymidine (18F-FLT)...

2016
Yajuan Sun Hongjuan Yu Jingquan Ma Peiou Lu

OBJECTIVE The aim of our study was to evaluate the role of 18F-FDG PET/CT integrated imaging in differentiating malignant from benign pleural effusion. METHODS A total of 176 patients with pleural effusion who underwent 18F-FDG PET/CT examination to differentiate malignancy from benignancy were retrospectively researched. The images of CT imaging, 18F-FDG PET imaging and 18F-FDG PET/CT integr...

2014
Martha Nowosielski Matthew D. DiFranco Daniel Putzer Marcel Seiz Wolfgang Recheis Andreas H. Jacobs Günther Stockhammer Markus Hutterer

OBJECTIVES Intra-individual spatial overlap analysis of tumor volumes assessed by MRI, the amino acid PET tracer [18F]-FET and the nucleoside PET tracer [18F]-FLT in high-grade gliomas (HGG). METHODS MRI, [18F]-FET and [18F]-FLT PET data sets were retrospectively analyzed in 23 HGG patients. Morphologic tumor volumes on MRI (post-contrast T1 (cT1) and T2 images) were calculated using a semi-a...

2017
Ke-Fei Dou Xiao-Jin Gao Bo-Qia Xie Yan Li Zuo-Xiang He Min-Fu Yang

BACKGROUND Myocardial 18F-deoxyglucose (18F-FDG) uptake has been observed to be enhanced in patients with coronary artery disease (CAD) under fasting conditions. However, whether the increased 18F-FDG is induced by myocardial ischemia and how to discriminate ischemic from physiological 18F-FDG uptake have rarely been investigated. METHODS Under fasting conditions, 18F-FDG PET imaging was perf...

2016
Fu-Li Wang Ye-Ying Tan Xiang-Min Gu Tian-Ran Li Guang-Ming Lu Gang Liu Tian-Long Huo

BACKGROUND The detection of solitary pulmonary nodules (SPNs) that may potentially develop into a malignant lesion is essential for early clinical interventions. However, grading classification based on computed tomography (CT) imaging results remains a significant challenge. The 2-[18F]-fluoro-2-deoxy-D-glucose (18F-FDG) positron emission tomography (PET)/CT imaging produces both false-positiv...

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