PURPOSE XAGE-1 was originally identified by the search for PAGE/GAGE-related genes using expressed sequence tag database and was shown to exhibit characteristics of cancer/testis-like antigens. Four transcript variants XAGE-1a, XAGE-1b, XAGE-1c, and XAGE-1d have been identified thus far. We recently identified XAGE-1b as a dominant antigen recognized by sera from lung adenocarcinoma patients. W...

A series of 15 monocationic bithiophenes and isosteres were prepared and subjected to in vitro antiproliferative screening using the full National Cancer Institute (NCI)-60 cell line panel, representing nine types of cancer. Among the nine types of cancer involved in a five-dose screen, non-small cell lung and breast cancer cell lines were the most responsive to the antiproliferative effect of ...

A novel sequence for reversible second-order nonlinear optical (NLO) molecular switching with protonation/deprotonation has been achieved and tuned as well. The NLO switching with first hyperpolarizabilities (beta(0)) as low as 14 x 10(-30) esu (Off-phase) and as large as 1189 x 10(-30) esu (On-phase) have been computed by using density functional theory (DFT). Remarkably large differences betw...

INTRODUCTION AND METHODS. PKC family of enzymes typically activated by phospholipid hydrolysis and calcium consists of 12 isozymes that can be further categorized into conventional, novel and atypical PKCs. It has been widely accepted that Ca 2+ -dependent (conventional) PKCs play a major role in synaptic plasticity. Changes in PKC distribution may play an important role in associative memory s...

In a production experiment (Experiment 1) and an acceptability rating one (Experiment 2), we assessed two factors, spatial position and salience, which may influence the production of relational descriptions (such as "the ball between the man and the drawer"). In Experiment 1, speakers were asked to refer unambiguously to a target object (a ball). In Experiment 1a, we addressed the role of spat...

OBJECTIVES The objective of the following study is to evaluate the interaction between the resin materials used in immediate dentin sealing (IDS) techniques and impression materials with two different techniques to eliminate the oxygen-inhibition layer. MATERIALS AND METHODS The occlusal dentin surface of 35 human molars was exposed. The teeth were used in two Groups: Group 1 - Impression wit...

© The Ecological Society of America www.frontiersinecology.org D (Figure 1a), road crossings (Figure 1b), and other engineered structures act as barriers to ecological processes in aquatic ecosystems worldwide. Consequently, these barriers affect upstream connectivity by blocking animal migrations (Figure 1c; Pépino et al. 2012); affect downstream connectivity by retaining nutrients (Figure 1d;...

Let S = Sym(Ω) be the group of all permutations of an infinite set Ω. Extending an argument of Macpherson and Neumann, it is shown that if U is a generating set for S as a group, respectively as a monoid, then there exists a positive integer n such that every element of S may be written as a group word, respectively a monoid word, of length ≤ n in the elements of U. Some related questions are n...

Here, we report the whole-genome sequence of Bacillus subtilis strain DKU_NT_01 isolated from traditional Korean food containing soybean (chung-gook-jang). The de novo genome of Bacillus subtilis strain DKU_NT_01 has one contig and G+C content of 55.4%, is 4,954,264 bp in length, and contains 5,011 coding sequences (CDSs).

Rhizopogon is a hypogeous fungal genus that grows in an ectomycorrhizal symbiosis mostly with members of the Pinaceae family and its worldwide distribution correlates with natural and exotic Pinaceae forests. In Iran, Rhizopogon species have received scant attention from collectors in the past and have not been adequately collected. Few older studies, report the presence of R. luteolus (Saber 1...