نتایج جستجو برای: 2 amino benzimidazole
تعداد نتایج: 2673039 فیلتر نتایج به سال:
Novel 2-substituted-6-[(4-substituted-1-piperidyl)methyl]-1H-benzimidazoles were designed and synthesized as Ebola virus inhibitors. The proposed structures of the new prepared benzimidazole-piperidine hybrids confirmed based on their spectral data CHN analyses. target compounds screened in vitro for anti-Ebola activity. Among tested molecules, 26a (EC50=0.93 ?M, SI = 10) 25a (EC50=0.64 20) pot...
in this article, simple, convenient synthesis of 2-aryl-1-arylmethyl-1h-1,3-benzimidazole (1,2-disubstitutedbenzimidazoles) via condensation of 1,2-phenylenediamine and aromatic aldehydes using sba-pr-so3h as a nanoporous solid acid catalyst in green protocol was reported.
The trace impurities discovered after extended storage of a 5-amino- benzimidazole library were determined as imidazo[4,5-g]quinazoline derivatives by extensive spectroscopic data analysis. The formation of this highly aromatic heterocyclic ring involved a novel multi-component reaction, using which several novel compounds were prepared. Its mechanism was deduced as a cascade of chemical transf...
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