BACKGROUND The current guidelines recommend 21-day adjunctive corticosteroid therapy for HIV-1-infected pneumocystis pneumonia patients (HIV-PCP) with moderate-to-severe disease. Whether shorter adjunctive corticosteroid therapy is feasible in such patients is unknown. METHODS We conducted a retrospective study to elucidate the proportion of patients with moderate and severe HIV-PCP who requi...

Postoperative pulmonary complication (PPC) remains the most common postoperative complication in patients undergoing noncardiac thoracic surgery. We conducted the clinical study to determine the diagnostic role of miRNA-21 in noncardiac thoracic surgery. 368 patients undergoing noncardiac thoracic surgery were recruited. Blood samples were collected before anesthesia and 2 hours after incision ...

If, in some cataclysm, all of scientific knowledge were to be destroyed, and only one sentence passed on to the next generations of creatures, what statement would contain the most information in the fewest words? I believe it is the atomic hypothesis (or the atomic fact, or whatever you wish to call it) that all things are made of atoms—little particles that move around in perpetual motion, at...

The purpose of the research was to examine the effects of Trypanosoma brucei infection on different stages of gestation in female albino rats (Rattus norvegicus). The animals were divided into ten groups as follows: 15 animals infected on each of the following periods of pregnancy (days) 1-3, 4-6, 7-9, 10-12, 13-15, 16-18, and 19-21; 35 uninfected animals, out of which 10 were sacrificed immedi...

s/Presentations Ando, Proc ASCO 2003 Unspecified Unspecified 119 Japanese genotyped for UGT1A1*28 and UGT1A1 T3263G Not evaluated Severe tox 6.2-fold more likely in pts with both UGT1A1*28 and T3263G than in pts with wild-type UGT1A1 Chowbay, Proc ASCO 2003 100 mg/m, weekly Prospective 20 Chinese pts genotyped; 12 6/6, 6 6/7, and 2 7/7 No significant genotypedependent differences in irino, SN-3...

OBJECTIVES (1) To show that extracellular matrix deposition in 3-dimensional culture of human septal chondrocytes cultured in a rotary bioreactor is comparable to the deposition achieved under static culture conditions. (2) To demonstrate that the biomechanical properties of human septal chondrocytes cultured in a bioreactor are enhanced with time and are analogous to beads cultured under stati...

Forty-eight primiparous and pregnant Holstein cows at 202 (+/-59) days in milk and average daily milk production (DMP) of 22 (+/-5.3) kg at the beginning of the trial were used to study the possibility of identifying animals that are more responsive to recombinant bovine somatotropin (rbST). Animals were housed in free-stall barns, milked three times a day and fed a total mixed ration. Animals ...

AIM To evaluate the remineralization ability of two endodontic sealer cements. METHODOLOGY Mid-coronal dentine surfaces were subjected to: (i) 37% phosphoric acid (PA) or (ii) 0.5 mol L-1 ethylenediaminetetraacetic acid (EDTA) conditioning prior to the application of two experimental hydroxyapatite-based cements, containing sodium hydroxide (calcypatite) or zinc oxide oxiapatite respectively....