192 Wistar male rats (180200 g) were used to evaluate the prophylactic effect of ozone combined with antibiotics in septic shock model. The proinflammatory cytokines (IL-1β, TNFα, IL-6 and IL-2) expression were also determinated in different haemathopoyetic organs. The animals were taken at random and divided into 16 groups, 12 animals each: Group A, positive control (sepsis without treatment);...

High-temperature superconductivity in cuprates was discovered almost exactly 20 years ago, but a satisfactory theoretical explanation for this phenomenon is still lacking. The isotope effect has played an important role in establishing electron-phonon interaction as the dominant interaction in conventional superconductors. Here we present a unified picture of the oxygen isotope effect in cuprat...

Oxidative stress plays a vital role in dopaminergic neurodegeneration of Parkinson’s disease (PD). However, an antidiabetic drug, pioglitazone had shown a positive effectagainst oxidative stress to treat nervous unrest. Objective of this study is to evaluate the protective effect of Pioglitazone (25mg/kg/p.o) against 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) mice model of PD. The PD i...

in order to compare effect of magnetic field and frigate surfactant to enhance the efficacy of iodosulfuron-methyl-sodium plus mesosulfuron-methyl (chevalier) to control wild oat, a greenhouse experiment of dose-response was conducted. treatments were 0, 3, 6, 12, 18 and 24 doses g a.i. ha-1 of chevalier (i) without treatment, (ii) with frigate % 0.1 v/v, (iii) with magnetic field, and (iv) fri...

Blacks respond to therapy with amlodipine (AML) and hydrochlorothiazide (HCZ) with greater diuresis and natriuresis than whites, a situation that may lead to prerenal azotaemia and other problems. Although AML and HCZ are frequently used as antihypertensive agents in Nigeria, the effects of the combination treatment on renal function has been poorly examined. Therefore, to evaluate the effects ...

The kinetic deuterium isotope effect, D(V/K), on ethanol oxidation was measured by the radiometric, competitive method using 14C-labelled ethanol containing deuterium in the (1-R) position. Acetate was isolated and used for the determination. Experiments were performed on rats either anaesthetized and laparotomized, or provided with indwelling catheters in a. carotis, v. cava and v. portae. Exp...