The organic mol-ecule and uncoordinated water mol-ecule in the crystal of the title compound, C(25)H(24)N(4)O(4)·2H(2)O, both lie on special positions of twofold symmetry. A twofold rotation axis passes through the methyl-ene C atom connecting the two dihydro-benzopyrrolodiazepindionyl parts. The seven-membered C(5)N(2) ring adopts a boat conformation.

The title compound, [CuBr(C(9)H(9)N(5))](n), has been prepared by the solvothermal treatment of CuBr with 3-(2-allyl-2H-tetra-zol-5-yl)pyridine. It is a new homometallic Cu(I) olefin coord-ination polymer in which the Cu(I) atoms are linked by the 3-(2-allyl-2H-tetra-zol-5-yl)pyridine ligands and bonded to one terminal Br atom each. The organic ligand acts as a bidentate ligand connecting two n...

The 3-layer rhombohedral (3R) polytype of TaSe2-x Te x is known to display a superconducting transition temperature that is between 6 and 17 times higher than that of the two-layer hexagonal (2H) polytype. The remarkable difference in T c, although clearly associated with a difference in polytype, could have been due to an electronic effect specific to the Te-Se substitution. Here we report tha...

We investigated the antitumor activities of 5-fluorouracil (5-FU), 5'-deoxy-5-fluorouridine (5'-DFUR), 1-hexylcarbamoyl-5-fluorouracil (HCFU) and 1-(tetrahydro-2-furanyl)-5-fluorouracil (FT-207) in combination with hyperthermia in vitro. The antitumor effect of 5-FU (10(-4) M) was slightly enhanced by combination with hyperthermia (42 degrees C) for 2h, and the effect was determined to be addit...

The 2H magnetic relaxation dispersion (NMRD) technique was used to characterize interactions of dimethyl sulfoxide (DMSO) with globular proteins. A difference NMRD experiment involving the N-acetylglucosamine trisaccharide inhibitor, demonstrated that the DMSO 2H NMRD profile in lysozyme solution is due to a single DMSO molecule bound in the active cleft, with a molecular order parameter of 0.4...

A series of benzoxazine monomer supramolecules with different substituted groups on their benzene ring was prepared with a Mannich reaction and characterized by FTIR, 1H-NMR and MS. The obtained products were 3,4-dihydro-3-(2'-hydroxyethylene)-6-methyl-2H-benzoxazine (BM1), 3,4-dihydro-3-(2'-hydroxyethylene)-6-ethyl-2H-benz-oxazine (BM2), and 3,4-dihydro-3-(2'-hydroxyethylene)-6-methoxy-2H-benz...

(E)-5-(Methoxyimino)-1,3,4,5-tetrahydro-2H-benzo[b]azepin-2-one was prepared by a condensation reaction from 3,4-dihydro-1H-benzo[b]azepin-2,5-dione and O-methylhydroxylamine. The configuration at the C=N double bond determined X-ray crystallography.

We have developed a highly atom efficient synthesis of tetrasubstituted 3(2H)-furanones from easily accessible starting materials such as C,N-diarylaldonitrones and dibenzoylacetylene. Control experiments revealed that reaction aldonitrones having electron-withdrawing groups on the C-aryl substituent in polar aprotic solvents exhibited high product selectivity while temperature has only negligi...