www.sciencemag.org (this information is current as of January 5, 2009 ): The following resources related to this article are available online at http://www.sciencemag.org/cgi/content/full/322/5907/1494 version of this article at: including high-resolution figures, can be found in the online Updated information and services, found at: can be related to this article A list of selected additional ...

Joel A. Krauser‡ and F. Peter Guengerich§ From the Department of Biochemistry and Center in Molecular Toxicology, Vanderbilt University School of Medicine, Nashville, Tennessee 37232-0146 Running title: Isotope Effects in P450 3A4 Testosterone Oxidation Address correspondence to: Prof. F. Peter Guengerich, Department of Biochemistry, Vanderbilt University School of Medicine, 638 Robinson Resear...

Ali Ahmadvand1 and Mohammad Reza Daliri2* 1School of Computer Engineering, Iran University of Science and Technology (IUST), Tehran, Iran 2Biomedical Engineering Department, School of Electrical Engineering, Iran University of Science and Technology (IUST), Iran *Corresponding author: Mohammad Reza Daliri, Biomedical Engineering Department, School of Electrical Engineering, Iran University of S...

Ginger L. Milne, Huiyong Yin, and Jason D. Morrow Division of Clinical Pharmacology, Departments of Medicine and Pharmacology Vanderbilt University School of Medicine, 23 Avenue South at Pierce Avenue, Nashville, TN 37232-6602 Address correspondence to: Jason D. Morrow M.D., Division of Clinical Pharmacology, Departments of Medicine and Pharmacology, Vanderbilt University School of Medicine, 23...

The lacY gene of Escherichia coli, which encodes the lac permease, has been modified by oligonucleotide-directed, site-specific mutagenesis such that each of the four histidine residues in the molecule is replaced with an arginine residue. Replacement of histidine-35 and histidine-39 with arginine has no apparent effect on permease activity. In contrast, replacement of either histidine-205 or h...

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INTRODUCTION Body surface mapping (BSM) can be used to identify the site of earliest endocardial activation of ventricular tachycardias (VTs). The multielectrode QRS morphology during VT is determined by both the site of earliest activation and the subsequent spread of electrical activation through the ventricles. This study investigated the relationship between the site of earliest endocardial...

Vapor pressure: 1.33×10 Pa (108.2°C) Partition coefficient: Log Pow = 3.18 (observed value) Degradability: Hydrolyzability: No Report Biodegradability: Poorly biodegradable (BOD=0%, 14 days) Solubility: Water: 137 mg/l (25°C) (observed value) Organic solvents: Soluble in acetone and benzene. Amount of production/import:(1998): 322 t (Production 0 t, Import 322 t) Usage: Raw material for synthes...