Terrestrial animals must conserve water and NaCl to survive dry environments. The kidney reabsorbs 95% of the sodium filtered from the glomeruli before sodium reaches the distal connecting tubules. Excess sodium intake requires the renal kallikrein-kinin system for additional excretion. Renal kallikrein is secreted from the distal connecting tubule cells of the kidney, and its substrates, low m...

via its interaction with SRP receptor (reviewed by Walter and Johnson, 1994). Why then does the CPY signal se-Department of Chemistry University of Massachusetts at Amherst quence function in yeast? The finding that CPY translocates posttranslationally, Amherst, Massachusetts 01003 as does prepro-␣-factor, in a yeast in vitro translocation system (Hansen and Walter, 1988), suggested to Bird et ...

The aryl hydrocarbon receptor (AhR) regulates expression of genes encoding drug/xenobiotic metabolizing enzymes. Cytochrome P450 (CYP) 3A5 is involved in drug metabolism. However, regulation CYP3A5 gene not yet well understood. In this study, we aimed to investigate the effect ligands AhR on expression. mRNA was induced by polycyclic aromatic hydrocarbons (PAHs) such as 3-methylcholanthrene (3M...

OCEANOGRAPHY AND HUMAN HEALTH Th is aticle as been pulished in O ceagraphy, Vlum e 9, N um er 2, a qurterly jornal of Th e O ceagraphy Soiety. Coyright 2006 by Th e O ceagraphy Soiety. A ll rhts rerved. Perm ision is gnted to cpy his aticle or se in teching nd rearch. Replication, sstem m tic repruction, or coective redirbution of ny prtion of his aticle by phocopy m acine, repsting, or oher m ...

We found that CPY production in Saccharomyces cerevisiae KS58-2D/pCY303 was increased by the addition of thiamine into the medium, while the addition of thiamine had no effect on cell growth. It became clear that the positive effect of thiamine was due to transcriptional increase, because the levels of CPYmRNA were increased according to the amount of thiamine added. Furthermore, it was suggest...