BACKGROUND & AIMS Disruption of the enteric glial cell (EGC) network is an early pathologic feature in Crohn's disease. To determine the contribution of antigen-specific CD8 and CD4 T cells to the breakdown of the EGC network, we studied specific autoimmune targeting of an ectopic antigen expressed by EGCs. METHODS Transgenic mice (GFAP-HA), which express the influenza hemagglutinin (HA) in E...

plant growth regulators (pgrs) are widely used for lodging control in winter wheat (triticum aestivum l.) grown at high n rates. although the introduction of semi-dwarf wheat cultivars had largely solved the problem of lodging, evidence was already accumu-lating that the timely application of a growth retardant such as chlormequat (ccc) or ethephon could increase the grain yield of wheat, by th...

The endocytotic c-type lectin receptor DEC-205 is highly expressed on immature dendritic cells. In previous studies, it was shown that antigen-targeting to DEC-205 is a useful tool for the induction of antigen-specific Foxp3(+) regulatory T cells and thereby can prevent inflammatory processes. However, whether this approach is sufficient to mediate tolerance in mucosal tissues like the gut is u...

Penelitian bertujuan untuk mendapatkan deskripsi klon ubi kayu membandingkannya dengan unggul nasional yaitu UJ 5. dilakukan pada tanaman umur 9 bulan setelah tanam atau saat masa panen yang bertempat di kebun percobaan Desa Muara Putih, Natar, Lampung Selatan. Berdasarkan pengamatan terhadap 19 kayu, didapatkan beberapa daya hasil tinggi. Klon tertinggi Daniel Cabang 40 49,59 t/ha, BL 8-1 48,8...

The role of the hematopoietic lineage-restricted minor histocompatibility (H) antigen HA-1 in renal allograft tolerance was explored. We obtained peripheral blood samples from three recipients of histocompatibility leukocyte antigen (HLA)-matched, HA-1-mismatched renal transplants, one of which had discontinued immunosuppression >30 yr ago while sustaining normal kidney function. Peripheral blo...

A field study was carried out at Chatabara village, Institute of Agricultural Sciences (IAS), Siksha “O” Anusandhan Deemed to be University, Bhubaneswar, Odisha during winter (rabi) season 2019–20 evaluate the effect different INM practices on productivity, profitability and nutrient acquisition by blackgram. Results showed that with 100% RDF+ FYM (5 t/ha) + Nutri-priming Mo P (Ammonium molybda...

To broaden the applicability of adoptive T-cell therapy for the treatment of hematologic malignancies, we aim to start a clinical trial using HA-1-TCR transferred virus-specific T cells. TCRs directed against the minor histocompatibility antigen (MiHA) HA-1 are good candidates for TCR gene transfer to treat hematologic malignancies because of the hematopoiesis-restricted expression and favorabl...

The study was carried out for two consecutive years (2005-06 to 2006-07) to evaluate the wheat response to five different levels (0, 4, 8, 12 and 16 kg ha) of manganese (Mn) alongwith 150-100-60 kg NPK ha application. The experiment was laid out in randomized complete block design (RCBD) with three repeats under irrigated conditions at Agriculture Research Farm Karor, District Layyah. NPK was a...

Although somatically mutated autoantibodies are characteristic of many autoimmune diseases, the processes that can lead to their development remain poorly understood. We have examined the formation of autoreactive memory B cells in PevHA mice, which express the influenza virus PR8 hemagglutinin (HA) as a transgenic membrane bound neo-self-Ag. Using a virus immunization strategy, we show that PR...

the objective of this study was to evaluate the effect of different levels of irrigation and nitrogen fertilizer on nitrate movement, yield, and water use efficiency (wp) of corn in no-till planting method. the research was conducted in two years as a randomized complete block design arranged in a split block treatment design with three replicates in the safiabad agricultural research center. i...