Objectives: Eβ-thalassemia, the most serious form of HbE syndromes, may develop pre-diabetes (PD) and diabetes mellitus (DM), together constituting abnormal glucose homeostasis (AGH) as an endocrinopathy. This study aims to assess AGH prevalence pathogenesis in this thalassemia subtype. Material Methods: A cross-sectional was conducted at a tertiary care hospital from February 2017 December 201...

PURPOSE Short sleep duration is associated with obesity. Urinary 6-sulfatoxymelatonin (6-OHMS), the principal metabolite of melatonin, is closely related with sleep. We evaluated the difference in urinary 6-OHMS levels between obese girls and normal weight girls, and the relationship of urinary 6-OHMS with other hormones regulating body weight and metabolism. METHODS A total of 79 girls (6.3 ...

Growing evidence supports that air pollution exposure has become a risk factor of type II diabetes mellitus through the induction insulin resistance (IR), but presented findings did not provide consistent relationship between and IR in temporal scale magnitude. Reported associated with exposure, branched-chain amino acids (BCAAs) blood might modify association IR. We took advantage an existing ...

4.3. (i) Since HomA(A (I),M) ∼= M (I) for a set I and ⊕ is exact, it is clear that HomA(A (I),−) is exact, i.e. A(I) is projective. (ii) “Only if” part: Let A(P ) = ⊕ p∈P Ap be the free A-module indexed by P and ψ : A (P ) → p be the A-homomorphism such that ψ(1p) = p. Then ψ is surjective. If P is projective, then ψ has a section, i.e. an A-homomorphism φ : P → A(P ) such that ψ ◦ φ = idP . Th...

intake of socially undesirable sucrosecontaining foods. These assumptions would never be reliable. Thus, we recommended caution when interpretation of results from this part of our study. The last point raised by Buyken and Liese was that alcohol intake may predict glycemic index of the diet and hence affect the estimates of glycemic index and glycemic load. The reported associations are relati...

BACKGROUND Prader-Willi syndrome (PWS) is often related to severe obesity and type-2 diabetes mellitus (T2DM). However, few studies, and none in Korea, have examined prevalence of T2DM and other variables in PWS. The aim of this study was to identify the prevalence and associated risk factors for T2DM in Korean patients with PWS. METHODS We performed a retrospective cohort study of the 84 PWS...

OBJECTIVE Insulin resistance (IR) and associated metabolic abnormalities are increasingly being reported in the adolescent population. Cut-off value of homeostasis model of assessment IR (HOMA-IR) as an indicator of metabolic syndrome (MS) in adolescents has not been established. This study aimed to investigate IR by HOMA-IR in urban Indian adolescents and to establish cut-off values of HOMA-IR...

BACKGROUND Insulin-resistance is associated with cardiovascular disease but it is not used as a marker for disease in clinical practice. AIMS To study the association between the homeostatic model assessment (HOMA-IR) and triglyceride/HDLc ratio (TG/HDLc) with the presence of coronary artery disease in patients submitted to cardiac catheterization. METHODS In a cross-sectional study, 131 pa...

OBJECTIVE We compared South Asians with four other racial/ethnic groups in the U.S. to determine whether sociodemographic, lifestyle, or metabolic factors could explain the higher diabetes prevalence and whether insulin resistance and β-cell dysfunction occurred at younger ages and/or lower adiposity levels compared with other groups. RESEARCH DESIGN AND METHODS We performed a cross-sectional...

BACKGROUND Obesity seems to be linked to the hypothalamic involvement in craniopharyngioma. We evaluated the pre-surgery relationship between the degree of this involvement on magnetic resonance imaging and insulin resistance, as evaluated by the homeostasis model insulin resistance index (HOMA). As insulin-like growth factor 1, leptin, soluble leptin receptor (sOB-R) and ghrelin may also be in...