BACKGROUND Utility values are a key component of a cost-utility analysis. The EQ-5D and SF-6D are two commonly used measures for deriving utilities. Of particular importance is assessing the performance of these instruments in terms of validity. OBJECTIVES This study aimed to compare the performance of the EQ-5D and the SF-6D in different states of breast cancer. PATIENTS AND METHODS This w...

BACKGROUND The aim of this study was to assess the acceptability, reliability, validity and responsiveness of the Short-Form Health Survey (SF-12) and its preference-based derivative (SF-6D), the EQ-5D and the Neck Disability Index (NDI) in patients recovering from acute whiplash injury. METHODS Data from the Managing Injuries of the Neck Trial of 3,851 patients with acute whiplash injury for...

We report the first seven-dimensional quantum dynamics study for the dissociative chemisorption of H2O on Cu(111) using the time-dependent wave-packet approach, based on an accurate nine-dimensional potential energy surface (PES), which is newly developed by neural network fitting to 80 000 density functional theory points. This seven-dimensional quantum model allows the examination of the infl...

In a previous study, we have developed several chicken monoclonal antibodies (mAbs) against Eimeria acervulina (EA) in order to identify potential ligand molecules of Eimeria. One of these mAbs, 6D-12-G10, was found to recognize a conoid antigen of EA sporozoites and significantly inhibited the sporozoite invasions of host T lymphocytes in vitro. Furthermore, some of these chicken mAbs showed c...

OBJECTIVE Compare the preference measures derived from the SF-36, based on the two Brazilian versions of the Short Form 6 Dimensions questionnaire-Brazil (SF-6D Brazil). METHODS Observational and transversal study. The following quality of life assessment instruments were applied: HAQ, SF-36, EQ-5D and SF-6D (1998 and 2002 versions). Descriptive statistics and correlation coefficients were us...

As the number of preference-based instruments grows, it becomes increasingly important to compare different preference-based measures of health in order to inform an important debate on the choice of instrument. This paper presents a comparison of two of them, the EQ-5D and the SF-6D (recently developed from the SF-36) across seven patient/population groups (chronic obstructive airways disease,...

We systematically investigate the finite set of possible gauge groups and matter content for N = 1 supergravity theories in six dimensions with no tensor multiplets, focusing on nonabelian gauge groups which are a product of SU(N) factors. We identify a number of models which obey all known low-energy consistency conditions, but which have no known string theory realization. Many of these model...

Anticonvulsant activity of 7-phenyl-5H-thiazolo[5,4-e][1,2,3,4]tetrazolo[5,1-c]pyrrolo[1,2-a][1,4]diazepine (5) and 7-phenyl-5H-thiazolo[5,4-e][1,3,4]triazolo[5,1-c]pyrrolo[1,2-a][1,4]diazepines (6a-d) was measured against pentylenetetrazole (PTZ)-induced seizures in mice. Intraperitoneal injections of different doses (12.5, 25 and 50 mg/kg, i.p.) of test compounds decreased PTZ-induced seizure...

technology, equipment and applications related to the automated assembly and robotics industries. Feature articles include updates on the latest manufacturing research, tutorials on a particular manufacturing technology and field reports on installed manufacturing technologies, all from a technical perspective. Each issue also includes additional brief articles, product announcements and event ...

> introduction: escherichia coli is one of the important pathogens in human with global importance. because of the necessity for identification and the use of novel antibacterial compounds against e. coli , in this present study we focused on the antibacterial effects of synthesized thiazole, imidazole and tetrahydropyridine derivatives on e. coli . methods : for evaluation of antibacterial eff...