We studied the effective spread of lidocaine to inactivate neural tissue in the frontal cortex of the rhesus monkey. Injections of 2% lidocaine at 4 microl/min were made while units were recorded 1 or 2 mm away. To inactivate units 1 mm away from the injection site 100% of the time, 7 microl of lidocaine had to be injected. To inactivate units 2 mm away from the injection site 100% of the time,...

AIMS To explore whether lidocaine has the synergistic effect with pingyangmycin (PYM) in the venous malformations (VMs) treatment. METHODS The mouse spleen was chosen as a VM model and injected with different concentration of lidocaine or PYM or jointly treated with lidocaine and PYM. After 2, 5, 8 or 14 days, the mouse spleen tissues were acquired for hematoxylin-eosin (HE) staining, transmi...

Endoscopic submucosal dissection (ESD) is an advanced therapy for early gastric neoplasm and requires sedation with adequate analgesia. Lidocaine is a short-acting local anesthetic, and intravenous lidocaine has been shown to have analgesic efficacy in surgical settings. The aim of this study was to assess the effects of intravenous lidocaine on analgesic and sedative requirements for ESD and p...

Aim: To compare the safety and efficacy of lidocaine and esmolol, in modifying the hemodynamic response to laryngoscopy and intubation. Design: Randomized, placebo-controlled, double-blind study was carried out in Fauji Foundation hospital Lahore from 1 st June 2012 to 31 st August 2012,after taking written informed consent from patients and permission from medical and ethical committee of hosp...

Phosphorus is known to be exported from leaves of apple (8, 9, 10), bean (4, 6, 11, 12, 13), chrysanthemum (1, 2), corn (11, 12), tomato (12) and squash (71). The present work with bean plants compares export following application by spray, leaf vein injection (4) and droplet (13) methods. Other factors investigated which affect absorption and subsequent translocation of the spray-applied phosp...