Binding of a partial proteolytic digest by V8 enzyme of the yeast site-specific recombinase Flp to its target site gives rise to DNA-protein complexes that are smaller than those produced by the full-sized protein. The smallest of these complexes (occupancy of one peptide monomer per site) contains either one of two polypeptides (32 and 28 kDa) of the V8 digestion mixture. The amino termini of ...

The notion of topographic features like ridges, trenches, hills, etc. is formed by visualising the 2D image function as a surface in 3D space. Hence, properties of such a surface can be used to detect features from images. One such property, the curvature of the image surface, can be used to detect features characterised by a sharp bend in the surface. Curvature based feature detection requires...

We report on the magnetoresistance characteristics of one-dimensional electrons confined in a single InAs quantum well sandwiched between AlSb barriers. As a result of a nanofabrication scheme that utilizes a 3-nm-shallow wet chemical etching to define the electrostatic lateral confinement, the system is found to possess three important properties: specular boundary scattering, a strong lateral...

We present results from global VLBI, VLBA,MERLIN and VLA observations of the quasar 3C395 at 5.0 GHz, global VLBI and VLBA observations at 8.4 GHz, and VLBI test observations at 22.2 GHz. These combinations allow us to obtain radio images with resolutions ranging from 0.2 to 200 milliarcseconds, which show the continuity of the radio structure of 3C395 from parsec to kiloparsec scales. On parse...

Human exonuclease 1 (hExo1) plays important roles in DNA repair and recombination processes that maintain genomic integrity. It is a member of the 5' structure-specific nuclease family of exonucleases and endonucleases that includes FEN-1, XPG, and GEN1. We present structures of hExo1 in complex with a DNA substrate, followed by mutagenesis studies, and propose a common mechanism by which this ...

A Monte Carlo simulation has been performed to track light rays in cylindrical fibres by ray optics. The trapping efficiencies for skew and meridional rays in active fibres and distributions of characteristic quantities for all trapped light rays have been calculated. The simulation provides new results for curved fibres, where the analytical expressions are too complex to be solved. The light ...

Two active areas of research in the field of integrated optics are the coupling of on-chip waveguides to off-chip optical fibers and the reduction of circuit size which is dominated by the minimum bend radius of waveguides. Traditional approaches using mask-based lithography involve the complex etching of micro-mechanical on-chip mounts for the fiber or total-internal-reflection facets for shar...

We present Chandra X-ray (0.2-8 keV) and Very Large Array radio (15 and 5 GHz) images of the γ-ray bright, superluminal quasar 0827+243. The X-ray jet bends sharply—by ∼ 90, presumably amplified by projection effects—5 from the core. Only extremely weak radio emission is detected between the nuclear region and the bend. The X-ray continuum spectrum of the combined emission of the knots is rathe...

We modified a 2-bend cystotome for continuous curvilinear capsulorhexis (CCC) in manual or phacoemulsification cataract surgery to improve the safety and ease of performance. A 26G needle was converted into a cystotome with 3 bends. In this retrospective study, the performance of modified 3-bend cystotome was compared with conventional 2-bend cystotome. During cataract surgery, in the 3-bend cy...