نتایج جستجو برای: acitretin
تعداد نتایج: 446 فیلتر نتایج به سال:
The deconvolution principle was used to evaluate the extent of absorption and first-pass elimination of selected drugs. In the first example, deconvolution of the portal blood profiles of etretinate (ET, a synthetic retinoid) indicated that there was significant gut-wall conversion of ET to acitretin (ETA, the primary metabolite of ET) during a 60-min intestinal perfusion of ET. In the second e...
INTRODUCTION We previously reported a cohort of elderly patients with concurrent development of debilitating prurigo nodularis, extreme and disabling pruritus with or without eczematous dermatitis, and keratoacanthomas in the presence of actinic damage. This report is a long-term follow through on patients who were successfully transitioned from cyclosporine, acitretin, and topical 5-fluorourac...
BACKGROUND Psoriasis is difficult at times to treat and treatment failures are not uncommon regardless of approach. With the advent of expensive biologic therapies for psoriasis there is increasing discussion on the cost efficacy of a given systemic or biologic agent. An alternative and overlooked aspect of cost efficacy is the cost that accrues from treatment failures. METHODS We review the ...
Background B-cell Chronic Lymphocytic Leukemia (CLL) is the most common leukemia diagnosed in adults in the western world. Multiple Myeloma (MM), a plasma cell neoplasm based in bone-marrow, comprises about 1% of all malignant tumours. These are two incurable disorders with treatments that focus on controlling the disease and symptoms rather than eradicating it. Synthetic analogues of Retinoic ...
INTRODUCTION Palmoplantar psoriasis is an uncommon clinical form of psoriasis. Although localized to the palms and soles, it has a considerable impact on the patient's function and quality of life. OBJECTIVES To study the effectiveness and safety of psoralen-UV-A (PUVA) therapy in palmoplantar psoriasis and investigate predictors of clinical response. MATERIAL AND METHODS We performed a ret...
We would like to submit the following correction to the published paper [1], the reason for this action is that the data in Table 3 were reanalyzed by one more accurate statistic method: On page 12, the sentence of paragraph three "OR and 95% CI were calculated by limited backward-LR (likelihood ratio) logistic regression analysis with adjustment by clinical variables" should be corrected into ...
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