INTRODUCTION Acne vulgaris is a multifactorial disease of the pilosebaceous unit characterized by the development of inflammatory (papules, pustules, cysts) and/or non inflammatory lesions (open and closed comedones) that may progress to scars. The increase of bacterial resistances, adverse effects and teratogenicity of retinoids and lack of response to usual therapies have led to investigate n...

BACKGROUND Twenty percent azelaic acid gel is recommended as a topical treatment for acne due to its favorable profile. AIM Our objective in this study was to evaluate the efficacy of 20% azelaic acid gel in the treatment of mild to moderate acne vulgaris. METHODS This was a double blind, randomized clinical trial. Sixty patients with mild to moderate acne vulgaris were selected randomly to...

Back ground: Self medication is a norm in our country. One factor probably contributing to this phenomenon is over the counter sale of almost all medication without any regulation. In our dermatology practice, we frequently encounter patients with acne vulgaris deteriorated by topical use of self medication. However, there is very little data to support this in our set up. Objective: To determi...

Acne vulgaris impairs the appearance of an individual and causes psychological irritation. Inflammatory acne lesion is caused by multifactor incorporates in each step of acne pathogenesis. In an attempt to archive inflammatory lesion treatment with the promise of prevention of acne vulgaris, randomized and double-blind studies on the comparison of the efficacies of topical formulations containi...

BACKGROUND Acne vulgaris has an important genetic predisposition, as well as keratosis pilaris. Clinical observations suggest that patients with keratosis pilaris have less frequent or less severe acne breakouts; however, we found no studies on this regard OBJECTIVE To determine if the presence of keratosis pilaris is associated with lower prevalence and severity of acne. METHODS A cross-se...

The multiple etiologic factors involved in acne make the use of various medications necessary to treat the condition. This study aimed to determine the efficacy of mupirocin and rifampin used with standard treatment in the management of acne vulgaris. In a multicentre, randomized controlled, triple-blinded study, a total of 105 acne patients, with a clinical diagnosis of moderate to severe acne...

BACKGROUND We believe that instances of neuroticism and common psychiatric disorders are higher in adults with acne vulgaris than the normal population. OBJECTIVE Instances of acne in adults have been increasing in frequency in recent years. The aim of this study was to investigate personality traits and common psychiatric conditions in patients with adult acne vulgaris. METHODS Patients wh...

Acne vulgaris is a multifactorial disease affecting a majority of the adolescent population. The objective of this study was to test for a correlation between fasting serum lipid profiles and levels of testosterone, insulin, leptin, and interleukin 1-beta (IL-1beta) and the incidence of severe acne vulgaris in obese adolescent females. Four groups of adolescent females were studied: obese with ...

Background - Mukhdushika (Acne vulgaris) is burning issue among young generation. It gives inferiority complex in social life. There are lots of medicines for acne vulgaris but the results not upto mark. Our aim to combat with simple herbal formulation. Randomised controlled trial preferred study.
 Methods – Aim: To evaluate efficacy combination Lodhradilep and Khadirashtak kwath managemen...

Introduction: Various factors are involved in the pathogenesis of acne vulgaris. Recently, G6PD deficiency has been proposed in the pathogenesis of acne. G6PD has an important role in the oxidant/antioxidant balance. According to this theory, antioxidants are used in the treatment of acne recently. The aim of this study was to evaluate G6PD deficiency in patient with acne vulgaris. Methods: The...