Introduction The first drug selected for treatment of gastro-oesophageal reflux disease (GERD) and prevention of the recurrence is a proton pump inhibitor (PPI), but recently, a potassium-competitive acid blocker (P-CAB) was put on the market in Japan. Its onset of effect is faster than PPI, and it takes more than 2 days to recover acid secretion after the withdrawal period. Therefore, unlike P...

We determined whether prostate specific antigen (PSA) would decrease with immediate antiandrogen switching from bicalutamide (BCL) to flutamide (FLT) in patients receiving combined androgen blockade for advanced prostate cancer. From 2002 to 2006, 20 patients who showed PSA failure after first-line hormonal therapy with a luteinizing hormone-release hormone (LH-RH) agonist and BCL were enrolled...

OBJECTIVE AND DESIGN Eighteen active acromegalics entered a prospective open study with cabergoline (CAB), a dopaminergic drug much more potent than bromocriptine (Br). METHODS CAB was administered for 6 months at doses ranging between 0.5 mg twice weekly and 0.5 mg/day. Clinical-anamnestic characteristics of the patients were: (i) sensitivity to dopamine agonist drugs (10 patients); (ii) res...

Controlled atmosphere brazing (CAB) is a state-of-the-art joining technology associated with high production rates of many products, including microchannel aluminum heat exchangers. The complex designs of highly augmented compact heat transfer surfaces impose very difficult requirements for a brazing process. Regardless of the fact that brazing is a highly developed engineering art, many state-...

Understanding fine root characteristics in relation to soil properties of bamboo–broadleaf mixed forests may help optimize belowground production management and ecological functions mixed-forest ecosystems. In this study, we compared four different forests: Castanopsis chinensis (Sprengel) Hance with moso bamboo (CCB), Alniphyllum fortunei (Hemsl.) Makino (AFB), Choerospondias axillaris (Roxb.)...