primary hypokalemic periodic paralysis is a familial channelopathy inherited as an autosomal dominant trait. the first attack of paralysis may be evolved at any age, but has been reported to be most common in the second decade, so that some authorities believe that an episodic weakness beginning after age 25 is almost never due to primary periodic paralysis. in this retrospective study, we revi...

BACKGROUND Diseases that cause acute flaccid paralysis (AFP) often progress rapidly, thus may cause life threatening complications, therefore, their diagnosis and cure are important. This study was carried out to investigate the causes of acute generalized weakness in children referred to Amirkola Children's Hospital, in Babol, Iran. METHODS In this case series, the epidemiological causes of ...

of molecular methods for enterovirus detection, there would be fewer isolates available in future years. To date, nearly 400 poliovirus isolates have been proven to be Sabin vaccine-like. Once the large number of isolates from NSW has been screened, over 950 enteroviruses will have been tested to exclude wild poliovirus. With the expected global eradication of wild poliovirus by the end of the ...

Background: Nigeria has made tremendous progress towards polio eradication. The country was removed from the list of polio endemic countries by the World Health Organization (WHO) in September 2015. The last cases of wild poliovirus (WPV) and circulating vaccine derived poliovirus (cVDPV) from acute flaccid paralysis (AFP) cases had onset of paralysis in July 2014 and May 2015 respectively. The...

Human enterovirus D68 (EV-D68) is known to be associated with mild to severe respiratory infections. Recent reports in the United States and Canada of acute flaccid paralysis (AFP) in children with detection of EV-D68 in respiratory samples have raised concerns about the aetiological role of this EV type in severe neurological disease. This case study is the first report of AFP following EV-D68...

PROBLEM The emergence of Zika virus has challenged outbreak surveillance systems in many at-risk, low-resource countries. As the virus has been linked with Guillain-Barré syndrome, routine data on the incidence of acute flaccid paralysis (AFP) may provide a useful early warning system for the emergence of Zika virus. APPROACH We documented all Zika virus outbreaks and cases in 21 Pacific Isla...

Detection and investigation of all cases of acute flaccid paralysis (AFP) in children below 15 years of age are among the criteria for poliomyelitis-free certification. In the absence of poliomyelitis the incidence of AFP is around 1 per 100,000 children aged < 15 years. In the Netherlands, surveillance of AFP began in October 1992 under the supervision of the Dutch Paediatric Surveillance Syst...

A 7 years old boy presenting with acute flaccid paralysis after Varicella zoster infection was diagnosed as having acute transverse myelitis on MRI. He recovered fully after treatment with intravenous corticosteroids and acyclovir. The occurrence of this condition during or following Varicella infection is uncommon. There are previously very few reported cases of post-Varicella acute transverse...