Celiac artery thrombosis with ischemia is a rare condition associated with risk factors for thrombosis or embolism. The manifestation is rare because of the large number of collaterals between the coeliac and superior mesenteric artery. Advanced pancreatic cancer may cause gradual occlusion with collaterals which needs special attention during pancreaticoduodenectomy. No case was reported with ...

BACKGROUND Continuous ischemia monitoring helps identify patients with acute, but often silent, myocardial ischemia. Evidence suggests nurses do not activate ischemia monitoring because they think it is difficult to use. ST-Map software incorporates graphic displays to make monitoring of ongoing ischemia easier. OBJECTIVES To determine if nurses' use of and attitude toward ischemia monitoring...

CONTEXT Acute pancreatitis due to pancreatic ischemia is a rare condition. CASE REPORT In this case report we describe a 57-year-old male who developed an acute necrotizing pancreatitis after running a marathon and visiting a sauna the same evening, with an inadequate fluid and food consumption during both events. CONCLUSIONS Pancreatic ischemia imposed by mechanical and physical stress and...

Intraarterial injection may result in acute ischemia and amputation. The authors describe the case of a 27-year-old man with an acute hand ischemia following intraarterial injection of a suspension of buprenorphine. Despite its initial severity, this case was successfully treated with iloprost, a stable prostacyclin analogue, and dextran-40, a low-molecular-weight dextran.

OBJECTIVE Myocardial ischemia affects mitochondrial functions, leading to ionic imbalance and susceptibility to ventricular fibrillation. Trimetazidine, a metabolic agent, is clinically used in anti-anginal therapy. METHODS In this study, the rats were orally treated by gavage with trimetazidine 10 mg/kg/d for 7 days, and the effects of trimetazidine on mitochondrial respiratory function, bio...

OBJECTIVE In acute myocardial ischemia changes within the QRS complex can add valuable information to that from the repolarization phase. This study evaluates three angles obtained from the main slopes of the R-wave within the QRS complex to assess acute myocardial ischemia. METHODS The QRS angles, denoted by ØR (R-wave angle), ØU (up-stroke angle) and ØD (down-stroke angle), were evaluated i...

BACKGROUND It is unknown if cardiac ischemia has any deleterious effect on the contractile properties of nonischemic, peripheral vascular beds. Thus, the objective of the present study was to determine whether acute myocardial ischemia results in peripheral vascular dysfunction. METHODS AND RESULTS This study characterized force maintenance and the sensitivity to acetylcholine (ACh)-mediated ...

BACKGROUND Prophylactic mineralocorticoid receptor (MR) antagonism with spironolactone (Sp) in rats completely prevents renal damage induced by ischemia. Because acute renal ischemia cannot typically be predicted, this study was designed to investigate whether Sp could prevent renal injury after an ischemic/reperfusion insult. METHODS Six groups of male Wistar rats were studied: rats that rec...

BACKGROUND/AIMS Measurement of serum lactate remains the most frequently applied laboratory investigation to diagnose acute mesenteric (intestinal) ischemia. The present review aims at critically questioning the widespread measurement of serum lactate to diagnose acute mesenteric ischemia in clinical practice and at drawing attention to more novel markers of intestinal ischemia. METHODS An el...

Combined acute renal and pulmonary failure has a very high mortality. In animals, lung injury develops after shock or visceral or renal ischemia. Alpha-melanocyte-stimulating hormone (alpha-MSH) is an antiinflammatory cytokine, which inhibits inflammatory, apoptotic, and cytotoxic pathways implicated in acute renal injury. We sought to determine if alpha-MSH inhibits acute lung injury after ren...