نتایج جستجو برای: adverse drug reactions adrs
تعداد نتایج: 850498 فیلتر نتایج به سال:
Harms of drugs are an important cause of mortality and morbidity. The use of pharmaceuticals always entails a risk of adverse events, often to an unknown extent, and increased drug utilization has made drug-related problems a common occurrence (1). It is, for instance, estimated that adverse drug reactions (ADRs) cause the European Union almost 200,000 deaths annually (2) and cost approximately...
Background and Objectives:To compare three different methods of signal detection applied to the Adverse Drug Reactions registered in the Iranian Pharmacovigilance database from 1998 to 2005. Materials and Methods:All Adverse Drug Reactions (ADRs) reported to Iranian Pharmacovigilance Center from March 1998 through January 2005, were included in the analysis. The data were analyzed based on thre...
INTRODUCTION Pharmacovigilance (PV) is designed to monitor drugs continuously after their commercialization, assessing and improving their safety profile. The main objective is to increase the spontaneous reporting of adverse drug reactions (ADRs), in order to have a wide variety of information. The Italian Drug Agency (Agenzia Italiana del Farmaco [AIFA]) is financing several projects to incre...
PURPOSE With the increase in vancomycin use, adverse drug reactions (ADRs) associated with vancomycin have been reported increasingly more often. However, the characteristics of cutaneous ADRs with and without systemic reactions (SRs) have not been described. This study investigated the characteristics of spontaneously reported and assessed ADRs associated with vancomycin by a pharmacovigilance...
The aim of the present study was to observe adverse drug reactions (ADRs) with respect to polypharmacy at tertiary care centre at Bastar, Jagdalpur (Government Medical College, Jagdalpur). A prospective, observational evaluation of the ADRs conducted over a period of 6 months in Department of Medicine in Government Medical College, Jagdalpur. During the study period, a total of about 4850 patie...
People in every country of the world are affected by adverse drug reactions (ADR) and it is estimated that at least 60% of ADRs are preventable (WHO fact sheet). Data from various studies have shown that about 20 80% of ADRs are preventable. Majority of hospitals in India do not have an ADR reporting and monitoring programme. Moreover, assessment of the impact and potential for prevention was l...
normal 0 false false false en-us x-none ar-sa microsoftinternetexplorer4 background: pharmacovigilance assesses the safety profile of drugs. its main aim is the increase of spontaneous reporting of adverse drug reactions (adrs).the italian drug agency (aifa; agenzia italianadel farmaco) is financing several projects to the aim of increasing reporting, and in calabria a pharmacovigilance informa...
Antipsychotics (APs) are psychotropic drugs that generally have a psycholeptic effect, capable of reducing psychotic symptoms and psychomotor agitation. This class is widely used in psychiatric practice, especially for the treatment psychosis schizophrenia other disorders. Most APs pass through biotransformation process, or metabolism, after they enter body before being eliminated. There three ...
BACKGROUND Cutaneous adverse drug reactions (ADRs) are the most common adverse reactions attributed to drugs. A systematic and effective approach to a patient with suspected drug eruption allows for prompt recognition, classification and treatment of cutaneous ADRs. A standardized and effective approach for objective causality assessment is necessary to make consistent and accurate identificati...
The potential benefits of mining social media to learn about adverse drug reactions (ADRs) are rapidly increasing with the increasing popularity of social media. Unknown ADRs have traditionally been discovered by expensive post-marketing trials, but recent work has suggested that some unknown ADRs may be discovered by analyzing social media. We propose three methods for extracting ADRs from for...
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