mycotoxins are secondary metabolites of molds and have adverse effects on humans, animals, and crops. those can cause illnesses and economic losses. aflatoxin m1 (afm1) is one of the mycotoxins produced from the hydroxylated metabolite of aflatoxin b1 (afb1). it can be found in milk or milk products obtained from livestock that have ingested contaminated feed. in this paper, recent studies were...

Abstract Mycotoxins are secondary metabolites produced by several fungal species and molds. Under favorable conditions like high temperature moisture, they contaminate a large number of food commodities regional crops during pre post-harvesting. Aflatoxin is the main mycotoxin that harm animal human health due to its carcinogenic nature. Aflatoxins mainly released Aspergillus flavus parasiticus...

Awareness that undesirable levels of aflatoxin in food and feed may have serious consequences for human and animal health is increasing. Aflatoxins, probably the most studied and widely known mycotoxins, were first noted in the early 1960s. They are among the most potent mutagenic substances known; there is extensive experimental and epidemiological evidence that they induce liver cancer (WHO, ...

The media claims for the consumption of natural resource-based food have gradually increased in both developing and developed countries. The interest in the safety of these products is partially due to the possible presence of toxigenic fungi acting as mycotoxin producers, such as aflatoxins produced during the secondary metabolism of Aspergillus flavus, A. parasiticus and A. nomius. Aflatoxins...

Background: In Nigeria, there is paucity of information on exposure to aflatoxin by lactating women and children. Aflatoxin (AFs) are potent carcinogens that are produced as secondary metabolites of strains of Aspergillus parasiticus and Aspergillus flavus that grow on important food crops such as groundnuts, maize and other oilseeds .Present study reports on the aflatoxin exposure of lactating...

In the Aspergillus flavus (A. flavus)-peanut pathosystem, development and metabolism of the fungus directly influence aflatoxin contamination. To comprehensively understand the molecular mechanism of A. flavus interaction with peanut, RNA-seq was used for global transcriptome profiling of A. flavus during interaction with resistant and susceptible peanut genotypes. In total, 67.46 Gb of high-qu...

In order to gain insight into the causal agents of aflatoxin contamination of maize in Italy, populations of Aspergillus flavus on maize produced in the most affected area were characterized. Forty-six percent of A. flavus, isolated from maize kernels collected in 5 districts of northern Italy between 2003 and 2010, were unable to produce detectable levels of aflatoxins. The genetic diversity o...

Aflatoxicosis has repeatedly affected Kenyans, particularly in the eastern region, due to consumption of contaminated maize. However, save for the cases of acute toxicity, the levels of sub-lethal exposure have not been adequately assessed. It is believed that this type of exposure does exist even during the seasons when acute toxicity does not occur. This study, therefore, was designed to asse...

Aflatoxins are carcinogenic mycotoxins produced by some species in the Aspergillus genus, such as A. flavus and A. parasiticus. Contamination of aflatoxins in corn profusely happens at pre-harvest stage when heat and drought field conditions favor A. flavus colonization. Commercial corn hybrids are generally susceptible to A. flavus infection. An ideal strategy for preventing aflatoxin contamin...

Aflatoxins pose a significant public health risk, decrease productivity and profitability hamper trade. To minimize aflatoxin contamination biocontrol technology based on atoxigenic strains of Aspergillus flavus that do not produce is used widely in the United States. The technology, with generic name Aflasafe, has been improved adapted for use Africa. Aflasafe products have developed or are cu...