Currently, some natural herbal extracts are believed to have a marked tumoricidal effect and low toxicity for normal tissues. We investigated the effect of relatively low molecular weight products extracted from the basidiomycete, Agaricus blazei Murill, on MethA tumor cell growth with the aim of producing synthetic derivatives based on these products. Inoculation of the low molecule fraction (...

Extending the knowledge on secondary metabolites and the effect of solvent of extraction in mushrooms, We investigated five mushrooms species; two cultivated edible (Agaricus bisporus (brown) and Agaricus bisporus (white); and three wild medicinal edible mushrooms Trametes versicolor, Ganoderma applanatum and Fomes fomentarius for total phenolic, total flavonoid and condensed tannins content. T...

With the rising awareness of a healthy lifestyle, natural functional foods have gained much interest as promising alternatives to synthetic functional drugs. Recently, wild Agaricus bisporus (Lange) Sing. Chaidam has been found and artificially cultivated for its thick fresh body and excellent taste, with its antioxidant and anti-hypoxic abilities unknown. In this work, the antioxidant potentia...

BACKGROUND The involvement of free radicals and oxidative stress in HIV infection has been extensively studied, and the benefits of antioxidant supplementation in animal studies have been demonstrated. However, few studies have demonstrated a benefit in clinical studies. OBJECTIVE To verify the effects of dietary supplementation with Agaricus sylvaticus, a mushroom rich in antioxidants, on th...

Agaricus bisporus is a secondary decomposer fungus and an excellent model for the adaptation, persistence and growth of fungi in humic-rich environments such as soils of temperate woodland and pastures. The A. bisporus serine proteinase SPR1 is induced by humic acids and is highly expressed during growth on compost. Three Spr1 gene silencing cassettes were constructed around sense, antisense an...

The aim of this study was to analyze yields, biological efficiency, earliness (expressed as days to first harvest), and precociousness and establish models for the mushroom growing according to these parameters. The experiment followed a double factorial design with four sources of calcium (calcitic limestone, calcitic limestone + gypsum, dolomitic limestone and dolomitic limestone + gypsum) an...

The aim of this minireview is to give an overview of the literature about the green mould disease of cultivated champignons (Agaricus bisporus) caused by Trichoderma species. The first significant green mould epidemic appeared in Northern Ireland in 1985, which was quickly followed by subsequent outbreaks in several countries. The symptoms of green mould appear as large patches of compost turni...