Patients in the intensive care unit frequently experience delirium, anxiety, and agitation, with a variety of treatments used. This article discusses the role of an alpha-adrenoceptor agonist, dexmedetomidine, and its clinical relevance and advantages for the agitated patient.

OBJECTIVE Circadian rhythm disturbances, like sundowning, are seen in dementia. Because the circadian rhythm is regulated by the biological clock, melatonin might be effective in the treatment of these disturbances. We systematically studied the effect of melatonin treatment in patients with dementia. In addition, we elaborate on the possible effects one might expect of melatonin treatment in p...

Background and Purpose—Transesophageal echocardiography (TEE) is the gold standard for the diagnosis of a patent foramen ovale in adults. In children, acoustic windows on transthoracic echocardiography (TTE) are better than in adults; thus, an invasive TEE may not be necessary. Our goal was to assess the validity of TTE with agitated saline injection for the diagnosis of a patent foramen ovale ...

BACKGROUND Behavioural disturbance, such as agitation, is a common feature of dementia, and causes significant problems and distress for carers. Snoezelen is increasingly used with people who have dementia, but there is limited evidence of its efficacy. OBJECTIVE This crossover randomised controlled study aimed to evaluate the effect of Snoezelen on the mood and behaviour of patients with dem...

BACKGROUND Lavender essential oil shows evidence of sedative properties in neurophysiological and animal studies but clinical trials of its effectiveness as a treatment of agitation in people with dementia have shown mixed results. Study methods have varied widely, however, making comparisons hazardous. To help remedy previous methodological shortcomings, we delivered high grade lavender oil in...

BACKGROUND The purpose of this study was to evaluate the reliability, effectiveness, and safety of modified right heart contrast transthoracic echocardiography (cTTE) in comparison with the traditional method. MATERIAL/METHODS We performed a modified right heart cTTE using saline mixed with a small sample of patient's own blood. Samples were agitated with varying intensity. This study protoco...

in a novel dual bed reactor fischer-tropsch synthesis was studied by using two diffrent cobalt catalysts. an alkali-promoted cobalt catalyst was used in the first bed of a fixed-bed reactor followed by a rutenuim promoted cobalt catalyst in the second bed. the activity, product selectivity and accelerated deactivation of the system were assessed and compared with a conventional single bed react...

Abstract: The selection of a suitable type of reactor for the reaction with enzymes immobilized on the carriers is extremely important to industry. In this study the possibility of using pre-selected cellulose-based carriers (Granocel) to conduct the reaction in a stirred batch reactor and a fixed-bed reactor was investigated. It was shown that non-activated Granocel did not undergo compression...

Recent advances in supercomputers and parallel solver techniques have enabled users to run large simulations problems using millions of processors. Techniques for multiphysics nuclear reactor core simulations are under active development in several countries. Most of these techniques require large unstructured meshes that can be hard to generate in a standalone desktop computers because of high...

throughout the present research, squash (cucurbita pepo) slices (0.4 cm thickness and 4 cm diameter) were blanched in a steam chamber for 4 min. following cooling to room temperature, the squash slices were dehydrated by use of a hotair dryer, under air temperature of 60°c up to moisture content of 0.1065 kg h2o per kg d.m. squash slices of specified weights were rehydrated by immersion in dist...