BackgroundThe real impact of bevacizumab maintenance as single agent in metastatic colorectal cancer (mCRC) remains unclear. SAKK-41/06 and PRODIGE-9 failed to demonstrate the non-inferiority superiority versus no maintenance, respectively, while AIO-KRK-0207 showed fluoropyrimidines for time strategy failure.MethodsBibliography electronic databases (PubMed, MEDLINE, Embase, Scopus, Web Science...

-Native Monterey pine (Pinus radiata) forests occur in five populations on the west coast of North America. High severity fire has been reported to be the main disturbance agent that initiates seedling establishment for this species. To investigate the impacts of fire in this ecosystem, age structure and fire history data were collected from the native Ano Nuevo Monterey pine forest near Santa ...

BACKGROUND To determine the prognostic role of selected microRNA (miRNA) polymorphisms in advanced gastric cancer (AGC). PATIENTS AND METHODS Six hundred and seventy-four AGC patients received 5-fluorouracil (F), leucovorin (L), oxaliplatin (O) or FL + cisplatin (P) or additional docetaxel (T) to FLO (FLOT) within four clinical trials. Polymorphisms of mir-26a1 (rs7372209), mir-27a (rs895819)...