Key words (–)-stemoamide - Stemona alkaloids Evans aldol reaction cross metathesis Riley oxidation Staudinger

In the accompanying publication (2), it is shown that the interaction of rabbit muscle aldolase and dihydroxyacetone phosphate yielded a product that could be visualized spectrophotometrically with properties consistent with an enzyme-substrate complex. Similar affinities were found for dihydroxyacetone phosphate with both native and carboxypeptidase-treated aldolase. It was of interest, theref...

The linear amino acid-catalyzed direct asymmetric intermolecular aldol reaction is presented; simple amino acids such as alanine, valine, isoleucine, aspartate, alanine tetrazole and serine catalyzed the direct catalytic asymmetric intermolecular aldol reactions between unmodified ketones and aldehydes with excellent stereocontrol and furnished the corresponding aldol products in up to 98% yiel...

a highly efficient and simple method for the preparation of α,α´-bis(arylidene)cycloalkanones under solvent-free conditions has been developed. the crossed-aldol condensation of cycloalkanones (1 eq.) with arylaldehydes (2 eq.) in the presence of 2.5 mol% of ionic liquid 1,3-disulfonic acid imidazolium hydrogen sulfate {[dsim]hso4} afforded the title compounds in high yields and short reaction ...

A highly enantioselective organocatalytic vinylogous aldol-cyclization cascade reaction of 3-alkylidene oxindoles to isatins has been achieved by using bifunctional organocatalysts. The unexpected intramolecular lactonization which follows the initial aldol reaction, leading to the cleavage of the oxindole ring and generation of enantioenriched spirooxindole dihydropyranones in good to excellen...

Abstract A batch reaction system (volume 1 L) for scaled-up production of 5-HMF-based adhesive precursor solutions from industrially available fructose syrup was developed. The stabilizing effect sodium dithionite addition demonstrated. With this system, no concentration steps are needed in the precursors wood composite board production. optimized a design experiment approach to achieve good co...